Dr David Hough
Publications
Marrott, N. L., Marshall, J. J. T., Svergun, D. I., Crennell, S. J., Hough, D. W., Danson, M. J. and van den Elsen, J. M. H., 2012. The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly. FEBS Journal, 279 (5), pp. 713-723.
Moore, V., Kanu, A., Byron, O., Campbell, G., Danson, M. J., Hough, D. W. and Crennell, S. J., 2011. Contribution of inter-subunit interactions to the thermostability of Pyrococcus furiosus citrate synthase. Extremophiles, 15 (3), pp. 327-336.
Nunn, C. E. M., Johnsen, U., Schonheit, P., Fuhrer, T., Sauer, U., Hough, D. W. and Danson, M. J., 2010. Metabolism of pentose sugars in the hyperthermophilic archaea sulfolobus solfataricus and sulfolobus acidocaldarius. Journal of Biological Chemistry, 285 (44), pp. 33701-33709.
Royer, S. F., Haslett, L., Crennell, S. J., Hough, D. W., Danson, M. J. and Bull, S. D., 2010. Structurally informed site-directed mutagenesis of a stereochemically promiscuous aldolase to afford stereochemically complementary biocatalysts. Journal of the American Chemical Society, 132 (33), pp. 11753-11758.
Payne, K. A. P., Hough, D. W. and Danson, M. J., 2010. Discovery of a putative acetoin dehydrogenase complex in the hyperthermophilic archaeon Sulfolobus solfataricus. FEBS Letters, 584 (6), pp. 1231-1234.
Posner, M. G., Upadhyay, A., Bagby, S., Hough, D. W. and Danson, M. J., 2009. A unique lipoylation system in the Archaea: lipoylation in Thermoplasma acidophilum requires two proteins. FEBS Journal, 276 (15), pp. 4012-4022.
Emptage, C. D., Knox, R. J., Danson, M. J. and Hough, D. W., 2009. Nitroreductase from Bacillus licheniformis:a stable enzyme for prodrug activation. Biochemical Pharmacology, 77 (1), pp. 21-29.
Bull, S. D., Danson, M. J., Hough, D. W. and Royer, S., 2009. Engineering stereocontrol into aldolase catalyzed reactions. Abstracts of Papers of the American Chemical Society, 238, 23-ORGN.
Daniel, R. M., Danson, M. J., Hough, D. W., Lee, C. K., Peterson, M. E. and Cowan, D. A., 2008. Enzyme stability and activity at high temperatures. In: Siddiqui, K. S. and Thomas, T., eds. Protein adaptation in extremophiles. New York, U. S. A.: Nova Science, pp. 1-34.
Al-Mailem, D. M., Hough, D. W. and Danson, M. J., 2008. The 2-oxoacid dehydrogenase multienzyme complex of Haloferax volcanii. Extremophiles, 12 (1), pp. 89-96.
Potter, J. A., Kerou, M., Lamble, H. J., Bull, S. D., Hough, D. W., Danson, M. J. and Taylor, G. L., 2008. The structure of Sulfolobus solfataricus 2-keto-3-deoxygluconate kinase. Acta Crystallographica Section D-Biological Crystallography, 64, pp. 1283-1287.
