Oncogenes and tumour suppressor genes

The resource below includes a series of Powerpoint slides (and a list of further reading) on how mutations in genes involved in regulating the cell cycle can lead to oncogenesis and cancer progression. It highlights the role of growth factor signalling pathways and gives examples of gene mutations (oncogenes) that disrupt these networks. It also details the role of two classical tumour suppressor proteins (p53 and retinoblastoma) in cancer progression.

Icon Powerpoint Oncogenes and tumour suppressor genes