Aims & Learning Objectives:
To familiarise the student with recent advances in the pharmacology of the central nervous system (CNS), and to examine selected topics in greater depth. After taking this unit, the student should demonstrate knowledge and understanding of the mechanisms of action and therapeutic uses of the major groups of centrally-acting drugs, and an appreciation of the current understanding of disease processes in the brain.
Content:
Selected topics covering recent advances in CNS pharmacology, such as: chronobiology and chronopharmacology, the rhythmicity of pathological processes and drug responses, jet lag, shift work, seasonal affective disorder. Neuromodulators and neurotransmitters including tachykinins, pancreatic polypeptides, opioids, cholecystokinin, vasopressin and oxytocin, abnormal peptides in Alzheimers disease.
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