To introduce students to the field of genome science. To have them understand the key topics in this area. To teach each topic using specific examples of biological questions or problems so that the students will appreciate the potential of genome science to address a broad range of research challenges.
After taking this course the student should be able to:
* explain the technical basis of the principle methodologies used in genome science and explain their major limitations;
* access and interrogate the vast, and increasing, amount of genomic information available;
* describe the problems associated with the collation and maintenance of databases;
* describe how genomics can be applied to address biological questions.
Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Problem solving T/F/A, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F.
How genome sequence information is acquired, annotated, and analysed. How gene expression can be measured and analysed on a genome wide scale. How the proteome of a cell type can be determined and analysed. How gene function can be assessed through functional genomics. How molecular variation in DNA sequence between individuals can be measured. How genome information can be integrated into a framework for understanding biological complexity.