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BB40184: Cell biology of metastasis

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Follow this link for further information on credits Credits: 6
Follow this link for further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Follow this link for further information on period slots Period: Semester 1
Follow this link for further information on unit assessment Assessment: CW 100%
Follow this link for further information on supplementary assessment Supplementary Assessment: Reassessment not allowed
Follow this link for further information on unit rules Requisites: Before taking this unit you must take BB20023 and take BB20160
Follow this link for further information on unit content Description: Aims:
To provide an overview of our current understanding of key cellular processes such as the maintenance of epithelial cell polarity and the control of cell migration. To describe how defects in the regulation of these process contribute to the metastatic behaviour of cancer cells. To summarise current methods used to study these processes and the advantages and limitations of these approaches.

Learning Outcomes:
After taking this course the students should be able to:
1. Describe the regulation of key cellular processes such as the formation and maintenance of epithelial cell polarity and the regulation of cell migration.
2. Explain how defects in the normal regulation these process might contribute to metastatic behaviour.
3. Assess the merits and limitations of the different experimental approaches used to study these processes.

Skills:
Learning and studying (T/F/A), information handling and retrieval (T/F/A), working independently (T/F), written communication (T/F/A) and oral communication (T/F/A).

Content:
Formation and maintenance of epithelial cell polarity, epithelial to mesenchymal transition, cell migration.
Follow this link for further information on programme availabilityProgramme availability:

BB40184 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1

BB40184 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc (hons) Biochemistry (Full-time) - Year 3
  • USBB-AKB06 : BSc (hons) Biochemistry with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 3
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • USBB-ANM02 : MBiochem (hons) Biochemistry (Full-time with Thin Sandwich Placements) - Year 4
  • USBB-AKM05 : MBiol (hons) Molecular and Cellular Biology (Full-time with Thick Sandwich Placement) - Year 4
  • RSBB-AFM07 : Integrated PhD Postgenomic Biosciences (Biosciences Route) (Full-time) - Year 1
  • TSBB-AFM03 : MRes Biosciences (Full-time) - Year 1
  • TSBB-AFM06 : MSc Biosciences (Full-time) - Year 1
  • TSBB-AFM09 : MSc Medical Biosciences (Full-time) - Year 1

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.