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CH30210: Future of drug discovery

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Chemistry
Follow this link for further information on credits Credits: 3
Follow this link for further information on unit levels Level: Honours (FHEQ level 6)
Follow this link for further information on period slots Period: Semester 2
Follow this link for further information on unit assessment Assessment: CW 20%, EX 60%, PR 20%
Follow this link for further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Follow this link for further information on unit rules Requisites: Before taking this unit you must take CH10191 and take CH10192
Follow this link for further information on unit content Description: Aims:
The impact that recent developments in biology, chemistry and automation will have on the drug discovery process will be discussed.

Learning Outcomes:
After taking this course the student will be able to:
* Appreciate the range of emerging techniques, scientific breakthroughs and economic factors that define the future of drug discovery;
* Understand how financial, legal, logistical, marketing and political decisions affect the drug discovery process;
* Realize the increasing range of 'biologic' drug molecules that are being developed to treat disease;
* Be aware of a range of cutting edge therapeutic areas and drug discovery programs that are currently being pursued within the pharmaceutical industry;
* Describe some examples of recent research in drug discovery.

Skills:
Numeracy (F, A), Problem solving (T, F A), Scientific writing (F, A), Independent working (F), Group working (F).

Content:
Discuss the new generation of biological drugs (e.g. antibody therapy, siRNA, peptide based drugs, etc..), biomarkers. Vaccination. Tools for cellular imaging. Clinical trials and risk assessment. Fragment based drug discovery. The ubiquitin pathway. Chemical genetics and proteomics. Structural biology and drug discovery. Testing in zebra-fish. Targeting protein-protein interactions. Systems biology and drug discovery. Six guest lectures from industrial experts involved in dealing with different phases of the drug discovery process will be given. A `Dragons Den' session will be delivered on a new drug that has recently been approved by the FDA. A `Dragons Den´┐Ż like project will be run where the student pitches their idea for a new drug candidate. An assessed poster describing the properties and mode of action of a new drug that has been approved in the previous year by the FDA.
Follow this link for further information on programme availabilityProgramme availability:

CH30210 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.