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CH30037: Synthesis of medicinal compounds

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Chemistry
Follow this link for further information on credits Credits: 3
Follow this link for further information on unit levels Level: Honours (FHEQ level 6)
Follow this link for further information on period slots Period: Semester 2
Follow this link for further information on unit assessment Assessment: EX 100%
Follow this link for further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Follow this link for further information on unit rules Requisites: Before taking this unit you must take CH20149 and in taking this unit you cannot take CH40037
Follow this link for further information on unit content Description: Aims & Learning Objectives:
To introduce and illustrate how advanced synthetic organic chemistry is used in the preparation of medicinally valuable compounds. After studying this Unit, students should be able to:
* Apply knowledge of protecting group strategy in the synthesis of complex biological molecules.
* Apply knowledge of retrosynthetic analysis to the forward design of biologically active molecules.
* Define reagents and strategies for the assembly of stereochemically defined molecules.
* Design rational analogues, or modified compounds from given starting chemicals.

Content:
The unit is designed to give a sound knowledge of contemporary organic synthesis set within the context of synthesising biologically active molecules. The unit will set in context retrosynthetic analysis, protecting group strategy and modern methodology by means of total synthesis.
Follow this link for further information on programme availabilityProgramme availability:

CH30037 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFM05 : MChem (hons) Chemistry for Drug Discovery (Full-time) - Year 3

CH30037 is Optional on the following programmes:

Department of Chemistry
  • USCH-AFB01 : BSc (hons) Chemistry (Full-time) - Year 3
  • USCH-AFB09 : BSc (hons) Chemistry with Education (Full-time) - Year 3
  • USCH-AKB02 : BSc (hons) Chemistry with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB02 : BSc (hons) Chemistry with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFM02 : MChem (hons) Chemistry (Full-time) - Year 3

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.