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CH40141: Topics in catalysis for organic synthesis

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Chemistry
Follow this link for further information on credits Credits: 3
Follow this link for further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Follow this link for further information on period slots Period: Semester 1
Follow this link for further information on unit assessment Assessment: EX 100%
Follow this link for further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Follow this link for further information on unit rules Requisites: Before taking this unit you must take CH20149 or take CH20150 and in taking this unit you cannot take CH30141 and while taking this unit you must take CH30071 or take CH30128
Follow this link for further information on unit content Description: Aims:
To describe and demonstrate recent techniques in the application of catalysis to the synthesis of organic molecules. To illustrate how either metal-complexes or organocatalysts can be applied to the asymmetric synthesis of valuable intermediates.

Learning Outcomes:
After studying the Unit, students should be able to:
* Describe a range of catalytic systems for achieving important synthetic transformations
* Account for the importance of asymmetric catalysis in organic synthesis
* Integrate catalytic techniques with retrosynthetic analysis to introduce new stereocentres to organic molecules
* Extend the principles encountered in the course to critical discussion of recent and potential advances in asymmetric catalysis
* Solve synthetic problems using the techniques introduced including the application of techniques to unseen situations.

Skills:
Problem solving (T, F, A), Scientific writing (F, A), Independent working (F).

Content:
The development of chiral Lewis acids and their application in a range of synthetic transformations. A complementary approach to asymmetric synthesis using organocatalysis. Enantioselective palladium and rhodium catalysed carbon-carbon bond forming processes. A review of recent developments in the area of catalysis applied to organic synthesis. The application of catalysis to the synthesis of complex molecules.
Follow this link for further information on programme availabilityProgramme availability:

CH40141 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AKM03 : MChem (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAM06 : MChem (hons) Chemistry for Drug Discovery with Study Year Abroad (Full-time with Study Year Abroad) - Year 4

CH40141 is Optional on the following programmes:

Department of Chemistry
  • TSCH-AFM04 : MSc Chemistry for Drug Discovery (Full-time) - Year 1

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.