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PA30168: Drug targets in the immune system

Follow this link for further information on academic years Academic Year: 2014/5
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
The aims of this unit are to provide a knowledge base of recent developments in understanding the immune system and its role in human diseases, and to examine how such understanding can lead to identification and exploitation of novel drug targets for future therapy.

Learning Outcomes:
On successful completion of this unit, the student should be able to: demonstrate knowledge and understanding of recently identified target molecules and processes in the immune system, give examples of the role of these targets in particular therapeutic areas and utilise a range of ICT and cognitive skills in acquiring knowledge and understanding and applying them to given situations.

Skills:
Scientific skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F).

Content:
Following an introduction and brief overview of earlier core units, a number of topics will be discussed using the general formula of molecular target linking to cellular process linking to therapeutic area.. Topics will be selected on the basis of their currency at a given time - examples may include IgE, NF?B, PI-3 kinase, IL-23, P2X7 receptors linking to mast cell degranulation, apoptosis, chemotaxis, inflammation, inflammasome processing linking to respiratory, inflammatory and autoimmune disease states such as allergy, rheumatoid arthritis, asthma.
Further information on programme availabilityProgramme availability:

PA30168 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences with Year long work placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Year 3)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences with Professional Placement (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences with Study year abroad (Year 4)
Department of Pharmacy & Pharmacology
  • USPA-AFB02 : BSc(Hons) Pharmacology (Year 3)
  • USPA-AKB02 : BSc(Hons) Pharmacology with Year long work placement (Year 4)

Notes:
* This unit catalogue is applicable for the 2014/15 academic year only. Students continuing their studies into 2015/16 and beyond should not assume that this unit will be available in future years in the format displayed here for 2014/15.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.