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 Academic Year: | 2018/9 |
| Owning Department/School: | Department of Chemical Engineering |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Certificate (FHEQ level 4) |
| Period: |
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| Assessment Summary: | EX 100% |
| Assessment Detail: |
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| Supplementary Assessment: |
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| Requisites: | |
| Description:
| Aims: To provide students with key concepts pertinent to bioprocess engineering that relate to the production of industrial products and services. Learning Outcomes: After successfully completing this unit students will be able to: * Translate biological concepts to modern process industries. * Rationally design biovehicles to deliver molecules to cells. * Calculate receptor affinity for ligands and receptor saturation in the context of molecule delivery. * Quantify cell growth kinetics as well as death kinetics and design conditions for optimal cell growth from culture conditions. * Numerically and graphically calculate product formation from enzymes (biological catalysts) and quantify biochemical thermodynamics for cell energy expenditure. * Carryout material balances on a cell. Skills: * Develop a knowledge base and industrial awareness of bioprocesses (T, F, A) * Be able to recognise and apply appropriate tools and methodologies to design bioprocesses (T, A) * Critically analyse information and problem solving (T, F, A) Content: * An introduction to forms and structures of lipids and applications to make biovehicles * An understanding of shape factor of micelles; critical micelle concentration * Uptake mechanisms; receptor-molecule kinetics; receptor saturation * DNA replication; cell growth kinetics (including death); modelling profiles * Protein synthesis; protein production, scale-up Enzyme kinetics; Michaelis-Menten profile; quantifying enzyme behaviour * Material balances; conversion of carbohydrates to carbon dioxide and water * Biochemical thermodynamics; Gibbs energy in the cell; enthalpy from reactions. |
| Programme availability: |
CE10079 is Compulsory on the following programmes:Department of Chemical Engineering
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