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MA30086: Medical statistics

Follow this link for further information on academic years Academic Year: 2018/9
Further information on owning departmentsOwning Department/School: Department of Mathematical Sciences
Further information on credits Credits: 6      [equivalent to 12 CATS credits]
Further information on notional study hours Notional Study Hours: 120
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period:
Semester 1
Further information on unit assessment Assessment Summary: CW 25%, EX 75%
Further information on unit assessment Assessment Detail:
  • Coursework (CW 25%)
  • Examination (EX 75%)
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take MA20227
Further information on descriptions Description: Aims:
To introduce the statistical terminology specific to medical applications; to describe a range of techniques suitable for use in typical medical problems; to focus on questions that are of particular interest to medical practitioners; and to emphasise the explanation of statistical ideas and methods to clinicians.

Learning Outcomes:
On completing the course, students will be able to:
* Recognise the key statistical features of a medical research problem, and, where appropriate, suggest a suitable study design;
* Summarize medical data and identify possible sources of bias;
* Use R to analyse data from routinely-collected health data sources, epidemiological studies, and clinical trials;
* Understand the ethical considerations and governance problems related to biomedical studies.

Skills:
Numeracy T/F A
Problem Solving T/F A
Written and Spoken Communication T/F A
Computing Skills T/F

Content:
Revision of statistical tests set in a medical context and introduction of non-parametric tests. Measures of risk inepidemiology; incidence and prevalence and formulation of hypothesis tests and confidence intervals. Methods of standardization and standardized mortality ratios. Demographic life tables. Diagnostic tests and measures of agreement. Design of medical experiments and ethical considerations. Clinical trials: phases I to IV of drug development and testing. Possible sources of bias in medical studies; randomization, blinding, patient withdrawals and "intent to treat" analysis. Observational studies; cohort and case-control studies. Relative risks and odds ratios; developing hypothesis tests and confidence intervals and interpretation. Sample size calculations. Survival analysis: censoring, life tables, survivor and hazard functions, Kaplan-Meier product limit estimator, log-rank test, Cox's proportional hazards model.
Further information on programme availabilityProgramme availability:

MA30086 is Optional on the following programmes:

Department of Biology & Biochemistry Department of Economics
  • UHES-AFB04 : BSc(Hons) Economics and Mathematics (Year 3)
  • UHES-AAB04 : BSc(Hons) Economics and Mathematics with Study year abroad (Year 4)
  • UHES-AKB04 : BSc(Hons) Economics and Mathematics with Year long work placement (Year 4)
  • UHES-ACB04 : BSc(Hons) Economics and Mathematics with Combined Placement and Study Abroad (Year 4)
Department of Mathematical Sciences
  • TSMA-AFM08 : MSc Modern Applications of Mathematics
  • TSMA-AWM14 : MSc Modern Applications of Mathematics
  • USMA-AFB15 : BSc(Hons) Mathematical Sciences (Year 3)
  • USMA-AAB16 : BSc(Hons) Mathematical Sciences with Study year abroad (Year 4)
  • USMA-AKB16 : BSc(Hons) Mathematical Sciences with Year long work placement (Year 4)
  • USMA-AFB13 : BSc(Hons) Mathematics (Year 3)
  • USMA-AAB14 : BSc(Hons) Mathematics with Study year abroad (Year 4)
  • USMA-AKB14 : BSc(Hons) Mathematics with Year long work placement (Year 4)
  • USMA-AFB01 : BSc(Hons) Mathematics and Statistics (Year 3)
  • USMA-AAB02 : BSc(Hons) Mathematics and Statistics with Study year abroad (Year 4)
  • USMA-AKB02 : BSc(Hons) Mathematics and Statistics with Year long work placement (Year 4)
  • USMA-AFB05 : BSc(Hons) Statistics (Year 3)
  • USMA-AAB06 : BSc(Hons) Statistics with Study year abroad (Year 4)
  • USMA-AKB06 : BSc(Hons) Statistics with Year long work placement (Year 4)
  • USMA-AFM14 : MMath(Hons) Mathematics (Year 3)
  • USMA-AFM14 : MMath(Hons) Mathematics (Year 4)
  • USMA-AAM15 : MMath(Hons) Mathematics with Study year abroad (Year 4)
  • USMA-AKM15 : MMath(Hons) Mathematics with Year long work placement (Year 4)
  • USMA-AKM15 : MMath(Hons) Mathematics with Year long work placement (Year 5)

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