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CH30037: Synthesis of medicinal compounds

Follow this link for further information on academic years Academic Year: 2019/0
Further information on owning departmentsOwning Department/School: Department of Chemistry
Further information on credits Credits: 3      [equivalent to 6 CATS credits]
Further information on notional study hours Notional Study Hours: 60
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period:
Semester 2
Further information on unit assessment Assessment Summary: EX-TH 100%*
Further information on unit assessment Assessment Detail:
  • Open Book Examination of 24 hours duration* (EX-TH 100%)

*Assessment updated due to Covid-19 disruptions
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take CH20149 OR take CH20150
In taking this module you cannot take CH40037
Further information on descriptions Description: Aims:
To introduce and illustrate how advanced synthetic organic chemistry is used in the preparation of medicinally valuable compounds.

Learning Outcomes:
After studying this Unit, students should be able to:
* Apply knowledge of protecting group strategy in the synthesis of complex biological molecules.
* Apply knowledge of retrosynthetic analysis to the forward design of biologically active molecules.
* Define reagents and strategies for the assembly of stereochemically defined molecules.
* Design rational analogues, or modified compounds from given starting chemicals.

Skills:
Problem solving (T, F, A), Scientific writing (F, A), Independent working (F).

Content:
The unit is designed to give a sound knowledge of contemporary organic synthesis set within the context of synthesising biologically active molecules. The unit will set in context retrosynthetic analysis, protecting group strategy and modern methodology by means of total synthesis.
Further information on programme availabilityProgramme availability:

CH30037 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AAB08 : BSc(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKB08 : BSc(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)
  • USCH-AFM05 : MChem(Hons) Chemistry for Drug Discovery (Year 3)

CH30037 is Optional on the following programmes:

Department of Chemistry

Notes: