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CH30065: Biosynthesis & biotransformations

Follow this link for further information on academic years Academic Year: 2019/0
Further information on owning departmentsOwning Department/School: Department of Chemistry
Further information on credits Credits: 3      [equivalent to 6 CATS credits]
Further information on notional study hours Notional Study Hours: 60
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period:
Semester 2
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take CH30128
Further information on descriptions Description: Aims:
To provide an introduction to advanced aspects of a topic of current interest in Organic Chemistry.

Learning Outcomes:
After studying this Unit, students should be able to:
* Provide examples of biosynthetic pathways.
* Describe how enzymes can be used to produce enantiomerically pure compounds.

Skills:
Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F).

Content:
Biotransformations. The use of enzymes in organic synthesis. Kinetic resolution with hydrolytic enzymes, and the preparation of enantiomerically enriched alcohols and acids. Enzymes in oxidation, reduction and C-C bond forming reactions. Biosynthetic pathways, including the biosynthesis of fatty acids and polyketides. Terpene biosynthesis, the shikimic acid pathway and the roles of pyridoxal phosphate in biosynthesis are also addressed.
Further information on programme availabilityProgramme availability:

CH30065 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AAB08 : BSc(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKB08 : BSc(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)
  • USCH-AFM05 : MChem(Hons) Chemistry for Drug Discovery (Year 3)

CH30065 is Optional on the following programmes:

Department of Chemistry Programmes in Natural Sciences
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Year long work placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 4)

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