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PA20320: Specialised integrated unit 3: management of respiratory diseases and dermatology

Follow this link for further information on academic years Academic Year: 2020/1
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 12      [equivalent to 24 CATS credits]
Further information on notional study hours Notional Study Hours: 240
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment: CW 30%, EX 70%
Further information on supplementary assessment Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: While taking this module you must take PA20318 AND take PA20319 AND take PA20321 AND take PA20322
Further information on descriptions Description: Aims:
To provide a comprehensive, integrated understanding of the design and development of medicines, their pharmacological actions in the body and the evidence-based approach to treatment of patients with the aim of promoting safe and effective outcomes in respiratory diseases and dermatological disorders.

Learning Outcomes:
After successfully completing this unit, the student pharmacist will be able to:
1. Describe the aetiology, epidemiology, pathophysiology and clinical symptoms of respiratory diseases and how they are diagnosed and treated.
2. Explain the impact of genetic variation on human health and techniques for its detection and analysis
3. Explain the pharmacology and mechanisms of action of medicines used for the treatment of respiratory and dermatological conditions and be able to critically evaluate structure-activity relationships, dose-response relationships, biomarkers of treatment and clinical outcomes
4. Understand the ADME, formulation and manufacturing challenges in the development and production of pulmonary and topical drug delivery systems
5. Describe the formulation and requirements of inhaled and topical dosage forms and their application in treating respiratory and dermatological conditions
6. Identify and utilise evidence-based approaches for the management of respiratory diseases and dermatological disorders.
7. Describe the role of the pharmacist in prescribing, administering and monitoring medication for patients with respiratory diseases and dermatological disorders
8. Evaluate the evidence base for the management of respiratory diseases and dermatological disorders.
9. Make appropriate clinical decisions in support of patients with respiratory diseases and dermatological disorders.
10. Apply structured consultation skills to the conditions studied in this unit.

Skills:
Scientific and practical skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F/A)
Study skills (T/F)
Handling information (T/F/A)
Written communication (T/F/A)
Scientific & practical skills (T/F/A)
Information & communication technology (ICT) (T/F)

Content:
Content to include:
Clinical Introduction and overview of therapeutic area - Problem-based learning case
* Pharmaceutics theme
- Biopharmaceutics of pulmonary drug delivery
- Deposition mechanisms in the lung
- Inhalation devices
- Biopharmaceutics of topical drug delivery to the skin
- Dermatological formulations. Emulsions, creams, ointments and other colloidal systems
- Biopharmaceutics of nasal, ocular and otic drug delivery
* Pharmacology theme
- Autonomic nervous system pharmacology
- Acute inflammation in respiratory allergy and asthma
- Gene transcription, inherited genetic diseases including cystic fibrosis.
* Medicinal Chemistry and drug design theme
- Drug design - Steroids (II), beta agonists, structure-activity relationships
- Chemistry of steroids (II)
* Clinical therapeutics theme
- Allergy, hay fever, asthma and COPD
- Inflammatory and infective skin diseases
- Wound management and dressings
- Clinical decision making in respiratory diseases and dermatology
* Simulation and practice-based learning in respiratory disease.
Further information on programme availabilityProgramme availability:
NB. Postgraduate programme information will be added when the postgraduate catalogues are published in August 2020

PA20320 is a Designated Essential Unit on the following programmes:

Department of Pharmacy & Pharmacology
  • USPA-AFM03 : MPharm(Hons) Pharmacy (Year 2)
  • USPA-AKM03 : MPharm(Hons) Pharmacy with integrated pre-registration year (Year 2)

Notes: