Department of Chemical Engineering


Contact details

Room: WH 7.24
Tel: 01225 383369

PhD supervision

Nuno is available to supervise research degrees in:

  • Rapid ultra-low cost diagnostics
  • Transformative microfluidic systems
  • Oscillatory flow mixing
  • Intensification gas-liquid systems
  • Zero-waste ozonation systems
  • Continuous meso-scale crystallisers


Dr Nuno Reis



Dr Reis has joined the department of Chemical Engineering as a Reader in 2016. His research interests cover the areas of ultra-low cost optical microfluidic technologies, process intensification, oscillatory flow mixing and generic bioprocess engineering. Previous to Bath he was a Lecturer at Loughborough University (2011-2016), and was a Research Associate/Fellow for 4.5 year at the University of Cambridge (2006-2011), which includes a prestigious Marie Curie Intra-European Fellowship in the period 2008-2010. He has a track record of research outcomes being commercially exploited.

Related posts


  • PhD in Chemical and Biological Engineering (2006) and ‘Licenciatura’ in Biological Engineering (2001), both awarded by University of Minho, Portugal


Dr Reis research is driven by his passion for developing transformative technologies that address a number of identified technological gaps in industry and healthcare diagnostics. This provides the focus to his multidisciplinary research that spans across research areas of healthcare diagnostics, photochemistry, advanced oxidation processes, anaerobic fermentations, and bioanalytics.
He has a track record of innovations and inventions in the area of point-of-care diagnostics and miniaturisation of biological assays, such as a ‘Lab in a briefcase’ for portable measurement of biomarkers feature on main cover of RSC’s Lab on a chip journal (Barbosa et al., Lab Chip, 2014,14, 2918 –2928); ‘Lab on a stick’ for rapid identification of bacteria and antibiotic susceptibility testing (Reis et al, Lab Chip, 2016,16, 2891 –2899); femtomolar detection of multiple protein biomarkers in optical microfluidic strips (Castanheira et al., Analyst, 2015,140, 5609–5618).

His pioneering work on interfacing affordable miniaturised test strips with smartphones (e.g. Barbosa et al., Biosensors and Bioelectronics 70, 2015, 5–146) has features on BBC Click programme dedicated to personalised medicine broadcasted worldwide in 2016 on BBC World and BBC Persia, and recognised by two highly commended awards in IChemE Global awards 2016.

The current research themes in his research group include:

  • Rapid diagnostics
  • Transformative microfluidic technologies
  • Oscillatory flow mixing
  • Continuous meso-scale crystallisers
  • Bioprocess Intensification


Book Sections

Ferreira, A. I., Castanheira, A. P., Chahin, R. G., Mackley, M. R.,, Edwards, A. D. and Reis, N. M., 2013. Extruded microfluidic immunoassays. In: Zengerle, R., ed. Proceedings of the 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, Freiburg, Black Forest, Germany, 27-31 October 2013. Royal Society of Chemistry, pp. 982-984.


Russo, D., Siciliano, A., Guida, M., Galdiero, E., Amoresano, A., Andreozzi, R., Reis, N., Li Puma, G. and Marotta, R., 2017. Photodegradation and ecotoxicology of acyclovir in water under UV254 and UV 254/H2O2 processes. Water Research, 122, pp. 591-602.

Barbosa, A. I. and Reis, N. M., 2017. A critical insight into the development pipeline of microfluidic immunoassay devices for the sensitive quantitation of protein biomarkers at the point of care. Analyst, 142 (6), pp. 858-882.

Pivetal, J., Pereira, F. M., Barbosa, A. I., Castanheira, A. P., Reis, N. M. and Edwards, A. D., 2017. Covalent immobilisation of antibodies in Teflon-FEP microfluidic devices for the sensitive quantification of clinically relevant protein biomarkers. Analyst, 142 (6), pp. 959-968.

Ejim, L. N., Yerdelen, S., McGlone, T., Onyemelukwe, I., Johnston, B., Florence, A. J. and Reis, N. M., 2017. A factorial approach to understanding the effect of inner geometry of baffled meso-scale tubes on solids suspension and axial dispersion in continuous, oscillatory liquid–solid plug flows. Chemical Engineering Journal, 308, pp. 669-682.

Mackley, M. R., Butler, S. A., Huxley, S., Reis, N. M., Barbosa, A. I. and Tembely, M., 2017. The observation and evaluation of extensional filament deformation and breakup profiles for Non Newtonian fluids using a high strain rate double piston apparatus. Journal of Non-Newtonian Fluid Mechanics, 239, pp. 13-27.

Spasiano, D., Russo, D., Vaccaro, M., Siciliano, A., Marotta, R., Guida, M., Reis, N. M., Li Puma, G. and Andreozzi, R., 2016. Removal of benzoylecgonine from water matrices through UV254/H2O2 process:reaction kinetic modeling, ecotoxicity and genotoxicity assessment. Journal of Hazardous Materials, 318, pp. 515-525.

Reis, N. M., Pivetal, J., Loo-zazueta, A. L., Barros, J. M. S. and Edwards, A. D., 2016. Lab on a stick:multi-analyte cellular assays in a microfluidic dipstick. Lab on a Chip, 16 (15), pp. 2891-2899.

Lucas, M. S., Reis, N. M. and Li Puma, G., 2016. Intensification of ozonation processes in a novel, compact, multi-orifice oscillatory baffled column. Chemical Engineering Journal, 296, pp. 335-339.

Ren, Y., Crump, C. M., Mackley, M. M., Li Puma, G. and Reis, N. M., 2016. Photo inactivation of virus particles in microfluidic capillary systems:microfluidic inactivation of virus particles. Biotechnology and Bioengineering, 113 (7), pp. 1481-1492.

Russo, D., Spasiano, D., Vaccaro, M., Cochran, K. H., Richardson, S. D., Andreozzi, R., Li Puma, G., Reis, N. M. and Marotta, R., 2016. Investigation on the removal of the major cocaine metabolite (benzoylecgonine) in water matrices by UV254/H2O2 process by using a flow microcapillary film array photoreactor as an efficient experimental tool. Water Research, 89, pp. 375-383.

Russo, D., Spasiano, D., Vaccaro, M., Andreozzi, R., Li Puma, G., Reis, N. M. and Marotta, R., 2016. Direct photolysis of benzoylecgonine under UV irradiation at 254 nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal, 283, pp. 243-250.

Castanheira, A. P., Barbosa, A. I., Edwards, A. D. and Reis, N. M., 2015. Multiplexed femtomolar quantitation of human cytokines in a fluoropolymer microcapillary film. Analyst, 140 (16), pp. 5609-5618.

Barbosa, A. I., Gehlot, P., Sidapra, K., Edwards, A. D. and Reis, N. M., 2015. Portable smartphone quantitation of prostate specific antigen (PSA) in a fluoropolymer microfluidic device. Biosensors and Bioelectronics, 70, pp. 5-14.

Reis, N. M. and Li Puma, G., 2015. A novel microfluidic approach for extremely fast and efficient photochemical transformations in fluoropolymer microcapillary films. Chemical Communications, 51 (40), pp. 8414-8417.

Pereira, F. M., Sousa, D. Z., Alves, M. M., Mackley, M. R. and Reis, N. M., 2014. CO 2 dissolution and design aspects of a multiorifice oscillatory baffled column. Industrial & Engineering Chemistry Research, 53 (44), pp. 17303-17316.

Barbosa, A. I., Castanheira, A. P., Edwards, A. D. and Reis, N. M., 2014. A lab-in-a-briefcase for rapid prostate specific antigen (PSA) screening from whole blood. Lab on a Chip, 14 (16), pp. 2918-2928.

Reis, N. M., Liu, Z. K., Reis, C. M. and Mackley, M. R., 2014. Hydroxypropyl methylcellulose as a novel tool for isothermal solution crystallization of micronized paracetamol. Crystal Growth and Design, 14 (7), pp. 3191-3198.

Elvira, K. S., Wootton, R. C. R., Reis, N. M., Mackley, M. R. and Demello, A. J., 2013. Through-wall mass transport as a modality for safe generation of singlet oxygen in continuous flows. ACS Sustainable Chemisty and Engineering, 1 (2), pp. 209-213.

Edwards, A. D., Reis, N. M., Slater, N. K. H. and Mackley, M. R., 2011. A simple device for multiplex ELISA made from melt-extruded plastic microcapillary film. Lab on a Chip, 11 (24), pp. 4267-4273.

Scheiff, F., Mendorf, M., Agar, D., Reis, N. and Mackley, M., 2011. The separation of immiscible liquid slugs within plastic microchannels using a metallic hydrophilic sidestream. Lab on a Chip, 11 (6), pp. 1022-1029.

Darton, N. J., Reis, N. M., Mackley, M. R. and Slater, N. K. H., 2011. Fast cation-exchange separation of proteins in a plastic microcapillary disc. Journal of Chromatography A, 1218 (10), pp. 1409-1415.

Reis, N. M., Chirgadze, D. Y., Blundell, T. L. and Mackley, M. R., 2009. The effect of protein–precipitant interfaces and applied shear on the nucleation and growth of lysozyme crystals. Acta Crystallographica Section D-Biological Crystallography, 65 (11), pp. 1127-1139.

Conference or Workshop Items

Talbot, S., Li Puma, G. and Reis, N., 2016. Photocatalysis for water remediation and energy production. In: 4th UK Solar Fuels Symposium, 2016, 2016-01-22 - 2016-01-22.

Talbot, S., Li Puma, G. and Reis, N. M., 2015. Illuminating brighter horizons:photocatalysis for water remediation and energy production. In: Loughborough University Research Conference, 2015, 2015-11-11 - 2015-11-11.

This list was generated on Thu Oct 19 14:48:44 2017 IST.