Dr David Carbery
Profile
Our research themes are primarily organic synthesis in nature, however, they focus on a wide range of specific problems. Some of the particular areas are discussed below and cover topics such as helicity, organocatalysis, asymmetric synthesis, target orientated synthesis and development of new methodologies.
Research Interests
- New Ireland-Claisen Chemistry
- Divinyl Ketones
- Metal-Free Hydrogenation
Publications
Murray, A. T., Challinor, J. D., Gulácsy, C. E., Lujan, C., Hatcher, L. E., Pudney, C. R., Raithby, P. R., John, M. P. and Carbery, D. R., 2016. Modelling flavoenzymatic charge transfer events:development of catalytic indole deuteration strategies. Organic and Biomolecular Chemistry, 14 (15), pp. 3787-3792.
Carbery, D. R., Hill, M. S., Mahon, M. F. and Weetman, C., 2016. Facile kinetic induction of a dihydropyridide to pyrrolide ring contraction. Dalton Transactions, 45 (14), pp. 5925-5928.
Murray, A. T., King, R., Donnelly, J. V. G., Dowley, M. J. H., Tuna, F., Sells, D., John, M. P. and Carbery, D. R., 2016. Symbiotic transition-metal and organocatalysis for catalytic ambient amine oxidation and alkene reduction reactions. ChemCatChem, 8 (3), pp. 510-514.
Murray, A. T., Dowley, M. J. H., Pradaux-Caggiano, F., Baldansuren, A., Fielding, A. J., Tuna, F., Hendon, C. H., Walsh, A., Lloyd-Jones, G. C., John, M. P. and Carbery, D. R., 2015. Catalytic amine oxidation under ambient aerobic conditions:mimicry of monoamine oxidase B. Angewandte Chemie-International Edition, 54 (31), pp. 8997-9000.
Murray, A. T., Frost, J. M., Hendon, C. H., Molloy, C. D., Carbery, D. R. and Walsh, A., 2015. Modular design of SPIRO-OMeTAD analogues as hole transport materials in solar cells. Chemical Communications, 51 (43), pp. 8935-8938.
Buchard, A., Carbery, D. R., Davidson, M. G., Ivanova, P. K., Jeffery, B. J., Kociok-Köhn, G. and Lowe, J. P., 2014. Preparation of stereoregular isotactic poly(mandelic acid) through organocatalytic ring-opening polymerization of a cyclic O-carboxyanhydride. Angewandte Chemie-International Edition, 53 (50), pp. 13858-13861.
Hendon, C. H., Carbery, D. R. and Walsh, A., 2014. Three-electron two-centred bonds and the stabilisation of cationic sulfur radicals. Chemical Science, 5 (4), pp. 1390-1395.
Carbery, D.R., 2014. Reduction of CåC and CåC by Noncatalytic Chemical Methods. In: Comprehensive Organic Synthesis II.Vol. 8. 2 ed. Elsevier, pp. 632-638.
Hendon, C. H., Tiana, D., Murray, A. T., Carbery, D. R. and Walsh, A., 2013. Helical frontier orbitals of conjugated linear molecules. Chemical Science, 4 (11), pp. 4278-4284.
Heffernan, S. J., Tellam, J. P., Queru, M. E., Silvanus, A. C., Benito, D., Mahon, M. F., Hennessy, A. J., Andrews, B. I. and Carbery, D. R., 2013. Double gold-catalysed annulation of indoles by enynones. Advanced Synthesis & Catalysis, 355 (6), pp. 1149-1159.
Heffernan, S. J., Beddoes, J. M., Mahon, M. F., Hennessy, A. J. and Carbery, D. R., 2013. Gold-catalysed cascade rearrangements of ynamide propargyl esters. Chemical Communications, 49 (23), pp. 2314-2316.
Fairhurst, N.W.G., Munday, R.H. and Carbery, D.R., 2013. Simple oxazolidine chiral diene ligands for enantioselective rh-catalyzed conjugate additions. Synlett, 24 (4), pp. 496-498.
Crittall, M.R., Fairhurst, N.W.G. and Carbery, D.R., 2012. Point-to-helical chirality transfer for a scalable and resolution-free synthesis of a helicenoidal DMAP organocatalyst. Chemical Communications, 48 (91), pp. 11181-11183.
Heffernan, S.J. and Carbery, D.R., 2012. Ireland-Claisen rearrangement of ynamides:Stereocontrolled synthesis of 2-amidodienes. Tetrahedron Letters, 53 (38), pp. 5180-5182.
Murray, A. T., Matton, P., Fairhurst, N. W. G., John, M. P. and Carbery, D. R., 2012. Biomimetic flavin-catalyzed aldehyde oxidation. Organic Letters, 14 (14), pp. 3656-3659.
Fairhurst, N. W. G., Mahon, M. F., Munday, R. H. and Carbery, D. R., 2012. Remote stereocontrol in [3,3]-sigmatropic rearrangements: Application to the total synthesis of the immunosuppressant mycestericin G. Organic Letters, 14 (3), pp. 756-759.
Harker, W. R. R., Carswell, E. L. and Carbery, D. R., 2012. Si-free enolate Claisen rearrangements of enamido substrates. Organic and Biomolecular Chemistry, 10 (7), pp. 1406-1410.
Tellam, J. P. and Carbery, D. R., 2011. Ireland-Claisen rearrangement of substrates bearing chiral enol ether units. Tetrahedron Letters, 52 (45), pp. 6027-6029.
Crittall, M. R., Rzepa, H. S. and Carbery, D. R., 2011. Design, synthesis, and evaluation of a helicenoidal DMAP Lewis base catalyst. Organic Letters, 13 (5), pp. 1250-1253.
Tellam, J. P. and Carbery, D. R., 2010. Development of the Ireland-Claisen rearrangement of alkoxy- and aryloxy-substituted allyl glycinates. Journal of Organic Chemistry, 75 (22), pp. 7809-7821.
Silvanus, A. C., Groombridge, B. J., Andrews, B. I., Kociok-Kohn, G. and Carbery, D. R., 2010. Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition of nucleophiles to divinyl ketones. Journal of Organic Chemistry, 75 (21), pp. 7491-7493.
Harker, W. R. R., Carswell, E. L. and Carbery, D. R., 2010. A practical protocol for the highly E-selective formation of aryl-substituted silylketene acetals. Organic Letters, 12 (16), pp. 3712-3715.
Marsh, B. J. and Carbery, D. R., 2010. Chemoselective sulfide oxidation mediated by bridged flavinium organocatalysts. Tetrahedron Letters, 51 (17), pp. 2362-2365.
Marsh, B. J., Heath, E. L. and Carbery, D. R., 2010. Organocatalytic diimide reduction of enamides in water. Chemical Communications, 47 (1), pp. 280-282.
Marsh, B. J. and Carbery, D. R., 2009. One-Pot o-Nitrobenzenesulfonylhydrazide (NBSH) Formation-Diimide Alkene Reduction Protocol. Journal of Organic Chemistry, 74 (8), pp. 3186-3188.
Silvanus, A. C., Heffernan, S. J., Liptrot, D. J., Kociok-Kohn, G., Andrews, B. I. and Carbery, D. R., 2009. Stereoselective double Friedel-Crafts alkylation of indoles with divinyl ketones. Organic Letters, 11 (5), pp. 1175-1178.
Pearson, M. S. M. and Carbery, D. R., 2009. Studies toward the photochemical synthesis of functionalized [5]- and [6]carbohelicenes. Journal of Organic Chemistry, 74 (15), pp. 5320-5325.
Tellam, J. P., Kociok-Kohn, G. and Carbery, D. R., 2008. An Ireland-Claisen Approach to beta-Alkoxy alpha-Amino Acids. Organic Letters, 10 (22), pp. 5199-5202.
Ylioja, P. M., Mosley, A. D., Charlot, C. E. and Carbery, D. R., 2008. An Ireland–Claisen rearrangement approach to β2,3-amino acids. Tetrahedron Letters, 49 (7), pp. 1111-1114.
