Department of Chemistry
 John Lowe

NMR Spectroscopist/Academic Lab Co-ordinator

1 South 0.46

Email: j.lowe@bath.ac.uk

Tel: +44 (0) 1225 383474

 

Dr John Lowe

Profile

I manage the nuclear magnetic resonance (NMR) facilities in chemistry. The department houses five extremely well-used solution state spectrometers, ranging from 250-500 MHz, and capable of the full range of modern state-of-the-art NMR experiments. As well as being actively involved in many areas of research across the department, particular current interests include:

  • Developing new NMR methodology to characterise porous materials (in collaboration with Prof Sean Rigby, Nottingham)
  • The use of NMR spectroscopy in reaction monitoring – for example in the study of the oxidation of biodiesel (with Dr Chris Chuck, Chemical Engineering)
  • Applications of multinuclear NMR spectroscopy in organometallic chemistry
  • Applications of diffusion ordered spectroscopy (DOSY)

Please feel free to contact me if you have any questions about the use of NMR spectroscopy in chemistry at Bath.

Publications

Cybulski, M., Nicholls, J., Lowe, J., Mahon, M. and Whittlesey, M., 2017. Catalytic Hydrodefluorination of Fluoroarenes Using Ru(IMe4)2L2H2 (IMe4 = 1,3,4,5-tetramethylimidazol-2-ylidene; L2 = (PPh3)2, dppe, dppp, dppm) Complexes. Organometallics, 36 (12), pp. 2308-2316.

Johns, M., Bernardes, A., Ribeiro De Azevêdo, E., Guimarães, F., Lowe, J., Gale, E., Polikarpov, I., Scott, J. and Sharma, R., 2017. On the subtle tuneability of cellulose hydrogels: implications for binding of biomolecules demonstrated for CBM 1. Journal of Materials Chemistry B, 5 (21), pp. 3879-3887.

Hall, A. M. R., Chouler, J. C., Codina, A., Gierth, P. T., Lowe, J. P. and Hintermair, U., 2016. Practical aspects of real-time reaction monitoring using multi-nuclear high resolution FlowNMR spectroscopy. Catalysis Science and Technology, 6 (24), pp. 8406-8417.

Hill, M. S., Johnson, A. L., Lowe, J. P., Molloy, K. C., Parish, J. D., Wildsmith, T. and Kingsley, A. L., 2016. Aerosol-assisted CVD of SnO from stannous alkoxide precursors. Dalton Transactions, 45 (45), pp. 18252-18258.

Espinal-Viguri, M., King, A. K., Lowe, J. P., Mahon, M. F. and Webster, R. L., 2016. Hydrophosphination of unactivated alkenes and alkynes using iron(II):catalysis and mechanistic insight. ACS Catalysis, 6 (11), pp. 7892-7897.

Riddlestone, I., Rajabi, N., Lowe, J., Mahon, M., Macgregor, S. A. and Whittlesey, M., 2016. Activation of H2 over the Ru-Zn bond in the Transition Metal-Lewis Acid Heterobimetallic Species [Ru(IPr)2(CO)ZnEt]+ (IPr = 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene). Journal of the American Chemical Society, 138 (35), pp. 11081-11084.

Tickell, D. A., Lampard, E. V., Lowe, J. P., James, T. D. and Bull, S. D., 2016. A Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template. Journal of Organic Chemistry, 81 (15), 6795–6799.

McKeown, P., Davidson, M.G., Lowe, J. P., Mahon, M. F., Thomas, L. H., Woodman, T. J. and Jones, M. D., 2016. Aminopiperidine based complexes for lactide polymerisation. Dalton Transactions, 45 (12), pp. 5374-5387.

Tickell, D., Lampard, E., Lowe, J., James, T. and Bull, S., 2016. Forthcoming. A Simple Protocol for NMR Analysis of the Enantiomeric Excess of Chiral Diols Using an Achiral Diboronic Acid Template.

Anker, M. D., Hill, M. S., Lowe, J. P. and Mahon, M. F., 2015. Alkaline- earth-promoted CO homologation and reductive catalysis. Angewandte Chemie-International Edition, 54 (34), pp. 10009-10011.

Jones, M., Brady, L., Mckeown, P. M., Buchard, A., Schafer, P. M., Thomas, L. H., Mahon, M. F., Woodman, T. J. and Lowe, J. P., 2015. Metal influence on the iso- and hetero-selectivity of complexes of bipyrrolidine derived Salan ligands for the polymerisation of rac-lactide. Chemical Science, 6 (8), pp. 5034-5039.

Yang, B., Lowe, J. P., Schweins, R. and Edler, K. J., 2015. Small angle neutron scattering studies on the internal structure of poly(lactide- co -glycolide)- block -poly(ethylene glycol) nanoparticles as drug delivery vehicles. Biomacromolecules, 16 (2), pp. 457-464.

Jones, M. D., Hancock, S. L., McKeown, P., Schäfer, P. M., Buchard, A., Thomas, L. H., Mahon, M. F. and Lowe, J. P., 2014. Zirconium complexes of bipyrrolidine derived salan ligands for the isoselective polymerisation of rac-lactide. Chemical Communications, 50 (100), pp. 15967-15970.

Buchard, A., Carbery, D. R., Davidson, M. G., Ivanova, P. K., Jeffery, B. J., Kociok-Köhn, G. and Lowe, J. P., 2014. Preparation of stereoregular isotactic poly(mandelic acid) through organocatalytic ring-opening polymerization of a cyclic O-carboxyanhydride. Angewandte Chemie-International Edition, 53 (50), pp. 13858-13861.

Sun, X., Xu, Q., Kim, G., Flower, S.E., Lowe, J., Yoon, J., Fossey, J.S., Qian, X., Bull, S.D. and James, T.D., 2014. A water-soluble boronate-based fluorescent probe for the selective detection of peroxynitrite and imaging in living cells. Chemical Science, 5 (9), pp. 3368-3373.

Davies, C. J. E., Lowe, J. P., Mahon, M. F., Poulten, R. C. and Whittlesey, M. K., 2013. Synthesis and small molecule reactivity of trans-dihydride isomers of Ru(NHC)2(PPh3)2H2 (NHC = N-Heterocyclic Carbene). Organometallics, 32 (17), pp. 4927-4937.

Shiko, E., Edler, K. J., Lowe, J. P. and Rigby, S. P., 2013. Probing hysteresis during sorption of cyclohexane within mesoporous silica using NMR cryoporometry and relaxometry. Journal of Colloid and Interface Science, 398, pp. 168-175.

Lyall, C., Uosis-Martin, M., Lowe, J., Mahon, M. F., Pantos, G. D. and Lewis, S. E., 2013. Aliphatic C–H activation with aluminium trichloride–acetyl chloride:Expanding the scope of the Baddeley reaction for the functionalisation of saturated hydrocarbons. Organic and Biomolecular Chemistry, 11 (9), pp. 1468-1475.

Segarra, C., Mas-Marzá, E., Lowe, J. P., Mahon, M.F., Poulten, R.C. and Whittlesey, M.K., 2012. Ring-expanded N-heterocyclic carbene complexes of rhodium with bifluoride, fluoride, and fluoroaryl ligands. Organometallics, 31 (24), pp. 8584-8590.

Chuck, C. J., Jenkins, R. W., Bannister, C. D., Han, L. and Lowe, J. P., 2012. Design and preliminary results of an NMR tube reactor to study the oxidative degradation of fatty acid methyl ester. Biomass and Bioenergy, 47, pp. 188-194.

Shiko, E., Edler, K.J., Lowe, J.P. and Rigby, S.P., 2012. Probing the impact of advanced melting and advanced adsorption phenomena on the accuracy of pore size distributions from cryoporometry and adsorption using NMR relaxometry and diffusometry. Journal of Colloid and Interface Science, 385 (1), pp. 183-192.

Ali Khan, M., Mahon, M. F., Lowe, J. P., Stewart, A. J. W. and Lewis, S. E., 2012. Valuable new cyclohexadiene building blocks from cationic η5-iron-carbonyl complexes derived from a microbial arene oxidation product. Chemistry - A European Journal, 18 (42), pp. 13480-13493.

Gopinathan, N., Greaves, M., Lowe, J. P., Wood, J. and Rigby, S. P., 2012. Determination of the location of coke in catalysts by a novel NMR-based, liquid-porosimetry approach. Journal of Colloid and Interface Science, 381 (1), pp. 164-170.

Chuck, C. J., Bannister, C. D., Jenkins, R. W., Lowe, J. P. and Davidson, M. G., 2012. A comparison of analytical techniques and the products formed during the decomposition of biodiesel under accelerated conditions. Fuel, 96, pp. 426-433.

Saggu, R., Morrison, B., Lowe, J. P. and Pringle, A. K., 2012. Interleukin-1beta does not affect the energy metabolism of rat organotypic hippocampal-slice cultures. Neuroscience Letters, 508 (2), pp. 114-118.

Chua, L. M., Hitchcock, I., Fletcher, R. S., Holt, E. M., Lowe, J. and Rigby, S. P., 2012. Understanding the spatial distribution of coke deposition within bimodal micro-/mesoporous catalysts using a novel sorption method in combination with pulsed-gradient spin-echo NMR. Journal of Catalysis, 286, pp. 260-265.

Willcocks, A. M., Robinson, T. P., Roche, C., Pugh, T., Richards, S. P., Kingsley, A. J., Lowe, J. and Johnson, A. J., 2012. Multinuclear copper(I) guanidinate complexes. Inorganic Chemistry, 51 (1), pp. 246-257.

Tong, L. H., Pengo, P., Clegg, W., Lowe, J. P., Raithby, P. R., Sanders, J. K. M. and Pascu, S. I., 2011. Complexes of aryl-substituted porphyrins and naphthalenediimide (NDI): Investigations by synchrotron X-ray diffraction and NMR spectroscopy. Dalton Transactions, 40 (41), pp. 10833-10842.

Hitchcock, I., Holt, E. M., Lowe, J. P. and Rigby, S. P., 2011. Studies of freezing-melting hysteresis in cryoporometry scanning loop experiments using NMR diffusometry and relaxometry. Chemical Engineering Science, 66 (4), pp. 582-592.

Ali Khan, M., Lowe, J. P., Johnson, A. L., Stewart, A. J. W. and Lewis, S. E., 2011. Accessing the antipodal series in microbial arene oxidation: a novel diene rearrangement induced by tricarbonyliron(0) complexation. Chemical Communications, 47 (1), pp. 215-217.

Hitchcock, I., Chudek, J. A., Holt, E. M., Lowe, J. P. and Rigby, S. P., 2010. NMR Studies of Cooperative Effects in Adsorption. Langmuir, 26 (23), pp. 18061-18070.

Perkins, E., Lowe, J., Edler, K. and Rigby, S., 2010. Studies of structure-transport relationships in biodegradable polymer microspheres for drug delivery using NMR cryodiffusometry. Chemical Engineering Science, 65 (2), pp. 611-625.

Lee, Y. S., Lowe, J. P., Gilby, E., Perera, S. P. and Rigby, S. P., 2010. The initial release of cisplatin from poly(lactide-co-glycolide) microspheres. International Journal of Pharmaceutics, 383 (1-2), pp. 244-254.

Haller, L. J. L., Mas-Marza, E., Moreno, A., Lowe, J. P., Macgregor, S. A., Mahon, M. F., Pregosin, P. S. and Whittlesey, M. K., 2009. Formation of [Ru(NHC)4(η2-O2)H]+: an unusual, high frequency hydride chemical shift and facile, reversible coordination of O2. Journal of the American Chemical Society, 131 (28), pp. 9618-9619.

Ledger, A. E. W., Slatford, P. A., Lowe, J. P., Mahon, M. F., Whittlesey, M. K. and Williams, J. M. J., 2009. Ruthenium xantphos complexes in hydrogen transfer processes: reactivity and mechanistic studies. Dalton Transactions, 4, pp. 716-722.

Perkins, E. L., Lowe, J. P., Edler, K. J., Tanko, N. and Rigby, S. P., 2008. Determination of the percolation properties and pore connectivity for mesoporous solids using NMR cryodiffusometry. Chemical Engineering Science, 63 (7), pp. 1929-1940.

Rigby, S. P., Chigada, P. I., Perkins, E. L., Watt-Smith, M. J., Lowe, J. P. and Edler, K. J., 2008. Fundamental studies of gas sorption within mesopores situated amidst an inter-connected, irregular network. Adsorption, 14 (2-3), pp. 289-307.

Richter, I., Minari, J., Axe, P., Lowe, J. P., James, T. D., Sakurai, K., Bull, S. D. and Fossey, J. S., 2008. Intramolecular cation-pi interactions control the conformation of nonrestricted (phenylalkyl)pyridines. Chemical Communications

This list was generated on Sun Oct 22 22:42:53 2017 IST.

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