Chemical Characterisation and Analysis Facility

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Contacts

For NMR spectroscopy enquiries, please contact:

Dr John Lowe
NMR Spectroscopist in Chemistry
j.lowe@bath.ac.uk
+44 (0) 1225 383474

Dr Tim Woodman
NMR Spectroscopist in Pharmacy and Pharmacology
t.woodman@bath.ac.uk
+44 (0) 1225 385555

Nuclear Magnetic Resonance (NMR)

Nuclear magnetic resonance (NMR) is arguably the most important analytical technique available to chemists. Although complex to describe in full, the technique can be thought of more simply as asking nuclei questions about their local environment and then listening to the response.

Some of the application areas where NMR can help include:

  • Confirmation of the successful synthesis of target compounds
  • Identification of unknown compounds, either from unexpected results or from natural products
  • Quantitation and purity assessment of samples

All aspects of solution state NMR are undertaken in the Facility, including, but not limited to, variable temperature studies, multinuclear work (e.g. 11B, 19F, 31P), molecular self-diffusion studies, 2 and 3D multinuclear experiments and kinetic experiments.

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Equipment

Department of Chemistry

The NMR facilities in the Department of Chemistry comprise of five instruments:

  • 250 MHz Bruker Avance for routine high-throughput experiments, mainly 1H, equipped with a 60 position automatic sample changer
  • 300 MHz Bruker Avance for routine use, also for equipped with a 60 position sample changer, but capable of the full range of standard 1D and 2D experiments and the detection of most NMR-active nuclei
  • 500 MHz Agilent ProPulse with a 96 position sample changer, temperature control in automation and a full range of nuclei including 19F
  • 400 MHz Bruker Avance for use by trained staff and students, capable of a wide range of multinuclear NMR experiments and used particularly for variable temperature spectroscopy
  • 500 MHz Bruker Avance II+, also used by trained staff and students for the acquisition of advanced multinuclear NMR spectra

Internal users

For information on NMR for University of Bath chemistry staff and students please see our internal chemistry NMR wiki pages.

Department of Pharmacy and Pharmacology

The NMR facilities in the Department of Pharmacy and Pharmacology are comprised of two instruments:

  • 400 MHz Bruker Avance III for routine use walk-up, mainly 1H and 13C experiments, equipped with a 60 position automatic sample changer
  • 500 MHz Bruker Avance III for more advanced NMR techniques, including 1D and 2D 19F and 15N experiments, also with a 60 position sample changer

Internal users

For information on NMR for University of Bath P&P staff and students please see our internal P&P NMR wiki pages.