Department for Health

Dr John Campbell

Prize Fellow in exercise oncology and immunology

Prize FellowPhD

1 West 5.123
Email: j.campbell@bath.ac.uk
Tel: +44 (0) 1225 38 5495

Supervision of early career researchers

Supervision of early career researchers John is happy to be contacted to discuss supervision of research projects in the area of exercise and cancer prevention.

Profile

John joined the Department for Health in 2016 as a Prize Fellow and is developing a research programme investigating the anti-cancer properties of exercise. John is collaborating with the Bath Royal United Hospital, as well as national and international collaborators, to investigate how exercise and other lifestyle factors influence cancer development.

Prior to undertaking his role as a Prize Fellow, John completed his PhD in 2010 at the School of Sport, Exercise and Rehabilitation Sciences at the University of Birmingham UK. During his PhD, John investigated the benefits of exercise on immunological competency, whereby he conducted numerous randomised-controlled trials to determine how exercise improved vaccination responses in humans. Following his PhD, John undertook 5 years of post-doctoral training at the Institute of Immunology and Immunotherapy at the University of Birmingham Medical School. During this time, John co-invented the world’s first near-patient test for measuring free light chains (Seralite, Abingdon Health Ltd) - biomarkers for diagnosing and monitoring monoclonal gammopathies including MGUS and multiple myeloma. John has received principle / co-investigator funding from the MRC, NIHR and numerous other funding bodies.

Professional memberships

  • International Society for Exercise Immunology
  • American College of Sports Medicine
  • British Society of Immunology
  • The Physiological Society UK
  • Associate Fellow of the Higher Education Academy

Active collaborative and industry links

  • Institute of Immunology and Immunotherapy, University of Birmingham, UK
  • Faculty of Health Sciences, University of Sydney, Australia
  • School of Sport, Health and Exercise Sciences, Loughborough University, UK
  • School of Kinesiology, Louisiana State University, USA
  • Radboud university medical centre Nijmegen, Netherlands
  • Abingdon Health Ltd, Birmingham, UK.

Research interests

  • Exercise oncology and immunology
  • Inflammation, ageing and cancer
  • Vaccination and immune competency
  • Lifestyle behaviours and cancer prevention
  • Biomarker and assay development

Publications

Jump to: Articles

Articles

Campbell, J. P., Heaney, J. L. J., Pandya, S., Afzal, Z., Kaiser, M. F., Owen, R. G., Child, J. A., Gregory, W. M., Morgan, G. J., Jackson, G. H., Bunce, C. M. and Drayson, M. T., 2017. Active multiple myeloma suppresses and typically eliminates coexisting MGUS. British Journal of Cancer

Heaney, J. L. J., Campbell, J. P., Yadav, P., Griffin, A. E., Shemar, M., Pinney, J. H. and Drayson, M. T., 2017. Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test. BMC Nephrology, 18 (1), 247.

Heaney, J. L. J., Campbell, J. P., Griffin, A. E., Birtwistle, J., Shemar, M., Child, J. A., Gregory, W. M., Cairns, D. A., Morgan, G. J., Jackson, G. H. and Drayson, M. T., 2017. Diagnosis and monitoring for light chain only and oligosecretory myeloma using serum free light chain tests. British Journal of Haematology, 178 (2), pp. 220-230.

Turner, J., Spielmann, G., Wadley, A., Aldred, S., Simpson, R. and Campbell, J., 2016. Exercise-induced B cell mobilisation:preliminary evidence for an influx of immature cells into the bloodstream. Physiology and Behavior, 164 (A), pp. 376-382.

Campbell, J. P., Heaney, J. L. J., Shemar, M., Baldwin, D., Griffin, A. E., Oldridge, E., Goodall, M., Afzal, Z., Plant, T., Cobbold, M., Jefferis, R., Jacobs, J. F. M., Hand, C. and Drayson, M. T., 2016. Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum κ and λ immunoglobulin free light chains (FLC):inception of a new near-patient FLC screening tool. Clinical Chemistry and Laboratory Medicine

Te Velthuis, H., Drayson, M. and Campbell, J. P., 2016. Measurement of free light chains with assays based on monoclonal antibodies. Clinical Chemistry and Laboratory Medicine, 54 (6), pp. 1005-1014.

Heaney, J. L. J., Phillips, A. C., Drayson, M. T. and Campbell, J. P., 2016. Serum free light chains are reduced in endurance trained older adults:Evidence that exercise training may reduce basal inflammation in older adults. Experimental Gerontology, 77, pp. 69-75.

Curran, M. C., Campbell, J. C., Drayson, M. D., Gleeson, M. G. and Narendran, P. N., 2016. Exploring the mechanisms through which exercise influences beta cell health in Type 1 diabetes. Diabetic Medicine, 33 (Suppl. 1), p. 76.

Campbell, J. P., Eijsvogels, T. M. H., Wang, Y., Hopman, M. T. E. and Jacobs, J. F. M., 2016. Assessment of serum free light chain levels in healthy adults immediately after marathon running. Clinical Chemistry and Laboratory Medicine, 54 (3), pp. 459-465.

Turner, J. E., Wadley, A., Aldred, S., Fisher, J., Bosch, J. A. and Campbell, J. P., 2016. Intensive exercise does not preferentially mobilise skin-homing T cells and NK cells. Medicine & Science in Sports & Exercise

Heaney, J. L. J., Gleeson, M., Phillips, A. C., Taylor, I. M., Drayson, M. T., Goodall, M., He, C.-S., Svendsen, I. S., Killer, S. C. and Campbell, J. P., 2016. Salivary immunoglobulin free light chains:reference ranges and responses to exercise in young and older adults. Exercise Immunology Review, 22, pp. 28-41.

Quinn, L. M., McWilliam, S., Campbell, J. P., Hughes, D. S., Drayson, M. T. and Narendran, P., 2015. Free light chains are a biomarker for cardiovascular disease in patients with Type 1 diabetes. Diabetic Medicine, 32 (S1), p. 84.

Brioli, A., Giles, H., Pawlyn, C., Campbell, J. P., Kaiser, M. F., Melchor, L., Jackson, G. H., Gregory, W. M., Owen, R. G., Child, J. A., Davies, F. E., Cavo, M., Drayson, M. T. and Morgan, G. J., 2014. Serum free immunoglobulin light chain evaluation as a marker of impact from intraclonal heterogeneity on myeloma outcome. Blood, 123 (22), pp. 3414-3419.

Turner, J. E., Campbell, J. P., Edwards, K. M., Howarth, L. J., Pawelec, G., Aldred, S., Moss, P., Drayson, M. T., Burns, V. E. and Bosch, J. A., 2014. Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults. Age, 36 (1), pp. 287-297.

Campbell, J., Heaney, J., Wang, Y., Cobbold, M., Goodall, M., Plant, T. and Drayson, M., 2014. New monoclonal antibodies detect all immunoglobulin free light chains in urine samples from over 13,000 patients. Clinical Chemistry, 60 (10), p. 16.

Campbell, J., Heaney, J., Patel, P., Goodall, M. and Drayson, M., 2014. New rapid urine test for the identification and quantitation of immunoglobulin free light chains (Bence Jones Proteins). Clinical Chemistry, 60 (10), p. 6.

Campbell, J., Stride, A., Heaney, J., Cobbold, M., Wang, Y., Goodall, M., Bonney, S., Chamba, A., Plant, T., Afzal, Z., Jefferies, R. and Drayson, M., 2013. Validation of a rapid lateral-flow test for the diagnosis and monitoring of immunoglobulin free light chains: Retrospective analysis of sera from patients with plasma cell dyscrasias. Clinical Chemistry, 59 (10), p. 14.

Turner, J. E., Bennett, S. J., Campbell, J., Bosch, J. A., Aldred, S. and Griffiths, H. R., 2013. The antioxidant enzyme peroxiredoxin-2 is depleted in lymphocytes seven days after ultra-endurance exercise. Free Radical Research, 47 (10), pp. 821-828.

Campbell, J. P., Wang, Y., Cobbold, M., Goodall, M., Bonney, S. L., Chamba, A., Birtwistle, J., Plant, T., Afzal, Z., Jefferis, R. and Drayson, M. T., 2013. Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine. Journal of Immunological Methods, 391 (1-2), pp. 1-13.

Campbell, J., Stride, A., Cobbold, M., Wang, Y., Goodall, M., Bonney, S., Chamba, A., Plant, T., Afzal, Z., Jefferis, R. and Drayson, M., 2013. Rapid test to identity myeloma kidney by measurement of serum free light chains. Clinical Lymphoma, Myeloma and Leukemia, 13, pp. 253-254.

Edwards, K. M., Pung, M. A., Tomfohr, L. M., Ziegler, M. G., Campbell, J. P., Drayson, M. T. and Mills, P. J., 2012. Acute exercise enhancement of pneumococcal vaccination response:a randomised controlled trial of weaker and stronger immune response. Vaccine, 30 (45), pp. 6389-6395.

Long, J. E., Ring, C., Drayson, M., Bosch, J., Campbell, J. P., Bhabra, J., Browne, D., Dawson, J., Harding, S., Lau, J. and Burns, V. E., 2012. Vaccination response following aerobic exercise:can a brisk walk enhance antibody response to pneumococcal and influenza vaccinations? Brain Behavior and Immunity, 26 (4), pp. 680-687.

Whitelegg, A. M. E., Birtwistle, J., Richter, A., Campbell, J., Turner, J. E., Ahmed, T. M., Giles, L. J., Fellows, M., Plant, T., Ferraro, A. J., Cobbold, M., Drayson, M. T. and MacLennan, C. A., 2012. Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay. Journal of Immunological Methods, 377 (1-2), pp. 37-46.

Edwards, K. M., Pung, M., Tomfohr, L., Campbell, J. P., Ziegler, M. G., Drayson, M. T. and Mills, P. J., 2011. A simple 15 min exercise task improves the antibody response to pneumococcal vaccination. Psychosomatic Medicine, 73 (3), pp. 59-60.

Campbell, J. P., Edwards, K. M., Ring, C., Drayson, M. T., Bosch, J. A., Inskip, A., Long, J. E., Pulsford, D. and Burns, V. E., 2011. Corrigendum to "The effects of vaccine timing on the efficacy of an acute eccentric exercise intervention on the immune response to an influenza vaccine in young adults" [Brain Behav. Immun. 24 (2010) 236-242]. Brain Behavior and Immunity, 25 (1), p. 174.

Edwards, K. M., Campbell, J. P., Ring, C., Drayson, M. T., Bosch, J. A., Downes, C., Long, J. E., Lumb, J. A., Merry, A., Paine, N. J. and Burns, V. E., 2010. Erratum to "Exercise intensity does not influence the efficacy of eccentric exercise as a behavioural adjuvant to vaccination" [Brain, Behavior, and Immunity 24, (2010), 623-630]. Brain Behavior and Immunity, 24 (7), p. 1220.

Long, J. E., Campbell, J., Burns, V., Bosch, J., Drayson, M., Ring, C. and Edwards, K., 2010. Eccentric exercise as an adjuvant to hepatitis B and meningitis ACWY vaccinations. Brain Behavior and Immunity, 24 (1), S33.

Edwards, K. M., Campbell, J. P., Ring, C., Drayson, M. T., Bosch, J. A., Downes, C., Long, J. E., Lumb, J. A., Merry, A., Paine, N. J. and Burns, V. E., 2010. Exercise intensity does not influence the efficacy of eccentric exercise as a behavioural adjuvant to vaccination. Brain Behavior and Immunity, 24 (4), pp. 623-630.

Campbell, J. P., Edwards, K. M., Ring, C., Drayson, M. T., Bosch, J. A., Inskip, A., Long, J. E., Pulsford, D. and Burns, V. E., 2010. The effects of vaccine timing on the efficacy of an acute eccentric exercise intervention on the immune response to an influenza vaccine in young adults. Brain Behavior and Immunity, 24 (2), pp. 236-242.

Campbell, J. P., Riddell, N. E., Burns, V. E., Turner, M., van Zanten, J. J. C. S. V., Drayson, M. T. and Bosch, J. A., 2009. Acute exercise mobilises CD8+ T lymphocytes exhibiting an effector-memory phenotype. Brain Behavior and Immunity, 23 (6), pp. 767-775.

Campbell, J. P., Guy, K., Cosgrove, C., Florida-James, G. D. and Simpson, R. J., 2008. Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain Behavior and Immunity, 22 (3), pp. 375-380.

This list was generated on Fri Oct 20 19:54:15 2017 IST.

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