# Ben Adams

## Profile

As a mathematical biologist I am interested in mathematics as a tool to study biological systems. These systems are often complex and multiscale. The objective is to abstract the key components and mechanisms of the system into a mathematical model. Analysis of this model can provide insights into how the system functions, lead to recommendations for system control or management and generate predictions for system behaviour. The development and analysis of these mathematical models may involve theory and techniques from diverse areas of mathematics including dynamical systems, partial differential equations, numerical methods, stochastic processes, computational simulation and statistics.

A wide range of biological systems interest me. However, the majority of my research is concerned with the epidemiology and evolution of infectious diseases. My work aims to address questions related to how seasonal variability, spatial heterogeneity and social structure influence a population’s vulnerability to epidemics, the way epidemics unfold, and how they may be controlled. I am also interested in the interaction between epidemiological dynamics and microbial evolution. These processes occur on similar timescales and their entanglement underscores the importance of accounting for evolution in strategies to manage infectious diseases.

I am a member of the Bath Centre for Mathematical Biology. Some of my work is about developing theory. But I also work with lab and field based researchers, developing mathematical models related to their observations and data. I am always open to new ideas for collaboration.

### Publications

Falcón-Lezama, J. A., Santos-Luna, R., Román-Pérez, S., Martínez-Vega, R. A., Herrera-Valdez, M. A., Kuri-Morales, Á. F., Adams, B., Kuri-Morales, P. A., López-Cervantes, M. and Ramos-Castañeda, J., 2017. Analysis of spatial mobility in subjects from a dengue endemic urban locality in Morelos State, Mexico. *PLoS ONE*, 12 (2), e0172313.

Falcon-Lezama, J., Velasco, M., Martinez, R., Castaneda, J. and Adams, B., 2016. Day-to-day population movement and the management of dengue epidemics. *Bulletin of Mathematical Biology*

Gaythorpe, K. and Adams, B., 2016. Disease and disaster:optimal deployment of epidemic control facilities in a spatially heterogeneous population with changing behaviour. *Journal of Theoretical Biology*, 397, pp. 169-178.

Adams, B., 2016. Household demographic determinants of Ebola epidemic risk. *Journal of Theoretical Biology*, 392, pp. 99-106.

Greenman, J. V. and Adams, B., 2015. The exclusion problem in seasonally forced epidemiological systems. *Journal of Theoretical Biology*, 367, pp. 49-60.

Woodall, H. and Adams, B., 2014. Partial cross-enhancement in models for dengue epidemiology. *Journal of Theoretical Biology*, 351, pp. 67-73.

Adams, B. and McHardy, A. C., 2011. The impact of seasonal and year-round transmission regimes on the evolution of influenza A virus. *Proceedings of the Royal Society B: Biological Sciences*, 278 (1716), pp. 2249-2256.

Omori, R. and Adams, B., 2011. Disrupting seasonality to control disease outbreaks:the case of koi herpes virus. *Journal of Theoretical Biology*, 271 (1), pp. 159-165.

Adams, B. and Boots, M., 2010. How important is vertical transmission in mosquitoes for the persistence of dengue? Insights from a mathematical model. *Epidemics*, 2 (1), pp. 1-10.

Omori, R., Adams, B. and Sasaki, A., 2010. Coexistence conditions for strains of influenza with immune cross-reaction. *Journal of Theoretical Biology*, 262 (1), pp. 48-57.

Adams, B. and Sasaki, A., 2009. Antigenic distance and cross-immunity, invasibility and coexistence of pathogen strains in an epidemiological model with discrete antigenic space. *Theoretical Population Biology*, 76 (3), pp. 157-167.

McHardy, A. C. and Adams, B., 2009. The role of genomics in tracking the evolution of influenza A virus. *PLoS Pathogens*, 5 (10), e1000566.

Adams, B. and Kapan, D. D., 2009. Man bites mosquito:understanding the contribution of human movement to vector-borne disease dynamics. *PLoS ONE*, 4 (8), e6763.

Cha, M., Mislove, A., Adams, B. and Gummadi, K. P., 2008. Characterizing social cascades in flickr. *In*: *First Workshop on Online Social Networks (WOSN'08)*, 2008-08-18.

Adams, B., McHardy, A. C., Lundegaard, C. and Lengauer, T., 2008. Viral bioinformatics. *In*: Frishman, D. and Valencia, A., eds. *Modern Genome Annotation.* Austria: Springer, pp. 429-452.