Department of Pharmacy and Pharmacology

sillhouette

Senior Lecturer

5 West 2.42

Email:  a.mcgrogan@bath.ac.uk

Tel: +44 (0) 1225 384142 

 

Dr Anita McGrogan 

Profile

Research Interests

My research interests are in medication utilisation and medication safety in vulnerable populations, especially those not usually included in phase III clinical trials. I also undertake research into epidemiology of autoimmune diseases and occurrence of serious outcomes. I am a statistician and develop statistical models for these research projects. Most of the research that I do uses anonymised primary care records from the Clinical Practice Research Datalink (CPRD).

Medication use and safety in pregnancy

This research group has considerable experience in carrying out medication utilisation and safety studies in pregnant women using CPRD data. We have our own algorithm to identify pregnancies and outcomes that has been developed and refined over many years. We have used this to evaluate the prescribing and safety of medications for epilepsy, diabetes, high cholesterol, depression and asthma during pregnancy.

Medication use and safety in older people

Older people, especially those with many comorbidities, do not participate in clinical trials therefore being able to use the CPRD to investigate disease occurrence, prescribing and medication safety gives considerable insight into the health of these populations especially very frail or the oldest patients. Areas of interest include dementia, rheumatoid diseases, cerebrovascular disease and diabetes.

Epidemiology of autoimmune diseases

Current work includes evaluating incidence, prevalence and outcomes associated with systemic sclerosis to try to better understand prognosis of this disease and its effects. As a rare disease, work is being undertaken to evaluate different statistical models to use in evaluating time to event models that incorporate both incident and prevalent cases of disease and outcomes.

Publications

McGrogan, A., Snowball, J. and Charlton, R., 2017. Statins during pregnancy: A cohort study using the General Practice Research Database to investigate pregnancy loss. Pharmacoepidemiology and Drug Safety, 26 (7), pp. 843-852.

Charlton, R., McGrogan, A., Snowball, J., Yates, L., Wood, A., Clayton-Smith, J., Smithson, H., Richardson, J., McHugh, N., Thomas, S., Baker, G. and Bromley, R., 2017. Sensitivity of the UK Clinical Practice Research Datalink to detect neurodevelopmental effects of medicine exposure in utero:comparative analysis of an antiepileptic drug exposed cohort. Drug Safety

Charlton, R., Klungsoyr, K., Neville, A., Jordan, S., de Jong-van den Berg, L., Bos, H., Puccini, A., Engeland, A., Gini, R., Davies, G., Hansen, A., Wang, H., McGrogan, A., Andersen, A., Dolk, H. and Garne, E., 2016. Prescribing of antidiabetic medicines before, during and after pregnancy:a study in seven European regions. PLoS ONE, 11 (5), e0155737.

Pauling, J. D., Shipley, J. A., Hart, D. J., McGrogan, A. and McHugh, N. J., 2015. Use of laser speckle contrast imaging to assess digital microvascular function in primary Raynaud phenomenon and systemic sclerosis:a comparison using the Raynaud condition score diary. The Journal of Rheumatology, 42 (7), pp. 1163-1168.

McGrogan, A., Snowball, J. and De Vries, C. S., 2014. Pregnancy losses in women with type 1 or type 2 diabetes in the UK:an investigation using primary care records. Diabetic Medicine, 31 (3), pp. 357-365.

Sammon, C. J., McGrogan, A., Snowball, J. and De Vries, C. S., 2013. Pandemic influenza vaccination during pregnancy:an investigation of vaccine uptake during the 2009/10 pandemic vaccination campaign in Great Britain. Human Vaccines and Immunotherapeutics, 9 (4), pp. 917-923.

Sammon, C. J., Snowball, J., McGrogan, A. and De Vries, C. S., 2012. Evaluating the hazard of foetal death following H1N1 inflenza vaccination:a population based cohort study in the UK GPRD. PLoS ONE, 7 (12), e51734.

McGrogan, A., Snowball, J. and De Vries, C., 2012. Major malformations in babies whose mothers had pre-existing diabetes during pregnancy. Pharmacoepidemiology and Drug Safety, 21 (S3), 838.

Sammon, C. J., McGrogan, A., Snowball, J. and De Vries, C. S., 2012. Factors associated with uptake of seasonal and pandemic influenza vaccine among clinical risk groups in the UK:an analysis using the General Practice Research Database. Vaccine, 30 (14), pp. 2483-2489.

Sammon, C. J., McGrogan, A., Snowball, J. and De Vries, C., 2011. Swine flu vaccination in pregnancy and associated miscarriage risk. Pharmacoepidemiology and Drug Safety, 20 (Supplement 1), S58-S59.

McGrogan, A., Franssen, C. F. M. and de Vries, C. S., 2011. The incidence of primary glomerulonephritis worldwide:a systematic review of the literature. Nephrology Dialysis Transplantation, 26 (2), pp. 414-430.

Sammon, C., McGrogan, A., Snowball, J. and De Vries, C., 2010. Factors predictive of H1N1 influenza vaccine uptake among ‘at-risk’ patients in the UK GeneralPractice Research Database. Pharmacoepidemiology and Drug Safety, 19 (S1), 31.

Bloomfield, K., John, N., McGrogan, A., Jones, R. and De Vries, C., 2010. Co-Prescribing of medications with anticholinergicproperties to those using cholinesterase inhibitors fordementia. Pharmacoepidemiology and Drug Safety, 19 (S1), 112.

McGrogan, A., Snowball, J. and De Vries, C., 2010. Pregnancy loss in patients with type 1 or type 2 diabetes during pregnancy. Pharmacoepidemiology and Drug Safety, 19 (S1), 498.

McGrogan, A., Sneddon, S. and de Vries, C. S., 2010. The incidence of Myasthenia Gravis:a systematic literature review. Neuroepidemiology, 34 (3), pp. 171-183.

McGrogan, A., Snowball, J. and De Vries, C., 2010. Treatment of diabetes before and during pregnancy. Pharmacoepidemiology and Drug Safety, 19 (S1), 156.

McGrogan, A., Snowball, J. and de Vries, C. S., 2009. Statins and pregnancy outcomes:A cohort study in the GPRD. Pharmacoepidemiology and Drug Safety, 18 (Supplement 1), S75-S76.

Terzakis, I. A., Snowball, J. M., McGrogan, A. and de Vries, C. S., 2009. Utilisation of psychotropic medicines in pregnancy. Pharmacoepidemiology and Drug Safety, 18 (Supplement 1), S78-S78.

McGrogan, A., Madle, G. C., Seaman, H. E. and de Vries, C. S., 2009. The epidemiology of Guillain-Barré syndrome worldwide. A systematic literature review. Neuroepidemiology, 32 (2), pp. 150-163.

McGrogan, A., Seaman, H. E., Wright, J. W. and de Vries, C. S., 2008. The incidence of autoimmune thyroid disease:a systematic review of the literature. Clinical Endocrinology, 69 (5), pp. 687-696.

Vroom, F., Snowball, J., McGrogan, A., de Jong-van den Berg, L. and de Vries, C., 2008. GPRD study of pregnancy outcomes following the prescribing of DMARDs. Pharmacoepidemiology and Drug Safety, 17 (Supplement 1), S227-S228.

This list was generated on Tue Oct 24 01:12:09 2017 IST.

View more publications »