Department of Pharmacy and Pharmacology

william-tillett

Senior Lecturer

5 West 2.18

Email:  w.tillett@bath.ac.uk

 

Dr William Tillett

Research interests

Williams current research interests centre on the assessment of psoriatic arthritis (clinical, radiographic and patient reported outcome), early detection of disease and treatment strategies.

Career

Dr William Tillett is a consultant rheumatologist at the Royal National Hospital for Rheumatic Diseases and senior lecturer in the Department of Pharmacy & Pharmacology. He graduated from the University of Bristol with a BSc in Anatomical Science before undertaking his medical degree at the same institution. He undertook his doctoral fellowship in outcome measurement in psoriatic arthritis.

William is the principle investigator or chief investigator on a variety of clinical and commercial trials and investigator initiated studies. Key impacts over the last five years have been the case for improved outcome with early detection of psoriatic arthritis, development and validation of clinical and radiographic measures of disease and understanding the real world effect medical treatment on outcomes important to patients.

William co-authored the 2013 BSR psoriatic arthritis anti-TNF guidelines and currently co-chairs the Psoriatic Arthritis Outcome Measurement in Rheumatology (OMERACT) working group.

He was awarded a EULAR Clinical Scientist award in 2015 for his work assessing the effect of pharmacological treatment of Psoriatic Arthritis.

William is a member of the international Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and is a trustee for the Bath Institute for Rheumatic Diseases (BIRD). 

Publications

Tillett, W., Dures, E., Hewlett, S., Helliwell, P. S., Fitzgerald, O., Brooke, M., James, J., Lord, J., Bowen, C., de Wit, M., Orbai, A.-M., McHugh, N. and , P. s. g., 2017. A Multicenter Nominal Group Study to Rank Outcomes Important to Patients, and Their Representation in Existing Composite Outcome Measures for Psoriatic Arthritis. The Journal of Rheumatology

Tillett, W., Orbai, A.-M., Ogdie, A., Leung, Y. Y., Strand, V., Gladman, D. D., Mease, P. J. and Coates, L. C., 2017. GRAPPA-OMERACT initiative to standardise outcomes in psoriatic arthritis clinical trials and longitudinal observational studies. Annals of the Rheumatic Diseases

Ogdie, A., de Wit, M., Callis Duffin, K., Campbell, W., Chau, J., Coates, L. C., Eder, L., Elmamoun, M., FitzGerald, O., Gladman, D. D., Goel, N., James, J. P., Kalyoncu, U., Latella, J., Lindsay, C., Mease, P. J., O'Sullivan, D., Steinkoenig, I., Strand, V., Tillett, W. and Orbai, A.-M., 2017. Defining Outcome Measures for Psoriatic Arthritis:A Report from the GRAPPA-OMERACT Working Group. The Journal of Rheumatology, 44 (5), pp. 697-700.

Tillett, W., Shaddick, G., Jobling, A., Askari, A., Cooper, A., Creamer, P., Clunie, G., Helliwell, P. S., James, J., Kay, L., Korendowych, E., Lane, S., Packham, J., Shaban, R., Thomas, M. L., Williamson, L. and McHugh, N., 2017. Effect of anti-TNF and conventional synthetic disease-modifying anti-rheumatic drug treatment on work disability and clinical outcome in a multicentre observational cohort study of psoriatic arthritis. Rheumatology, 56 (4), pp. 603-612.

Tillett, W., 2017. Composite Measures of Impact and Activity in Psoriatic Arthritis:A Conceptual Framework. The Journal of Rheumatology, 44 (3), pp. 268-270.

Dures, E., Hewlett, S., Lord, J., Bowen, C., McHugh, N. and Tillett, W., 2017. Important treatment outcomes for patients with psoriatic arthritis:a multisitequalitative study. The patient

Orbai, A.-M., de Wit, M., Mease, P. J., Callis Duffin, K., Elmamoun, M., Tillett, W., Campbell, W., FitzGerald, O., Gladman, D. D., Goel, N., Gossec, L., Hoejgaard, P., Leung, Y. Y., Lindsay, C., Strand, V., van der Heijde, D. M., Shea, B., Christensen, R., Coates, L., Eder, L., McHugh, N., Kalyoncu, U., Steinkoenig, I. and Ogdie, A., 2017. Updating the Psoriatic Arthritis (PsA) core domain set:A report from the PsA workshop at OMERACT 2016. The Journal of Rheumatology

Orbai, A.-M., de Wit, M., Mease, P., Shea, J. A., Gossec, L., Leung, Y. Y., Tillett, W., Elmamoun, M., Callis Duffin, K., Campbell, W., Christensen, R., Coates, L., Dures, E., Eder, L., FitzGerald, O., Gladman, D., Goel, N., Grieb, S. D., Hewlett, S., Hoejgaard, P., Kalyoncu, U., Lindsay, C., McHugh, N., Shea, B., Steinkoenig, I., Strand, V. and Ogdie, A., 2016. International patient and physician consensus on a psoriatic arthritis core outcome set for clinical trials. Annals of the Rheumatic Diseases

Campbell, W., Coates, L. C., Gladman, D. D., James, J., Lindsay, C. A., MacDonald, R., Moverley, A. R., Ogdie, A., Orbai, A.-M., O'Sullivan, D., Parkinson, A., Steinkoenig, I., Tillett, W. and Goel, N., 2016. Let's Talk about Inclusion:A Report on Patient Research Partner Involvement in the GRAPPA 2015 Annual Meeting. The Journal of Rheumatology, 43 (5), pp. 970-973.

Orbai, A.-M., Mease, P. J., de Wit, M., Kalyoncu, U., Campbell, W., Tillett, W., Eder, L., Elmamoun, M., FitzGerald, O., Gladman, D. D., Goel, N., Gossec, L., Lindsay, C. A., Steinkoenig, I., Helliwell, P. S., McHugh, N. J., Strand, V. and Ogdie, A., 2016. Report of the GRAPPA-OMERACT Psoriatic Arthritis Working Group from the GRAPPA 2015 Annual Meeting. The Journal of Rheumatology, 43 (5), pp. 965-969.

Tillett, W., Shaddick, G., Jadon, D., Robinson, G., Korendowych, E. and McHugh, N., 2016. Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis:A Proof-of-concept Study. The Journal of Rheumatology

Tillett, W. and Helliwell, P. H., 2016. The natural history of psoriatic arthritis. In: Adebajo, A., Boehncke, W.-H., Gladman, D. D. and Mease, P. J., eds. Psoriatic Arthritis and Psoriasis. Switzerland: Springer International Publishing, pp. 39-42.

Eder, L., Tillett, W. and Ritchlin, C. T., 2015. GRAPPA trainees symposium 2014:A report from the grappa 2014 annual meeting. Journal of Rheumatology, 42 (6), pp. 1016-1020.

Tillett, W., Eder, L., Goel, N., De Wit, M., Ogdie, A., Orbai, A. M., Campbell, W., Fitzgerald, O., McHugh, N. J., Gladman, D. D., Strand, V. and Mease, P. J., 2015. Review of the psoriatic arthritis working group at OMERACT 12:a report from the GRAPPA 2014 annual meeting. Journal of Rheumatology, 42 (6), pp. 1048-1051.

Jadon, D. R., Shaddick, G., Tillett, W., Korendowych, E., Robinson, G., Waldron, N., Cavill, C. and McHugh, N. J., 2015. Psoriatic Arthritis Mutilans:Characteristics and Natural Radiographic History. The Journal of Rheumatology

Tillett, W., Eder, L., Goel, N., De Wit, M., Gladman, D. D., FitzGerald, O., Campbell, W., Helliwell, P. S., Gossec, L., Orbai, A.-M., Ogdie, A., Strand, V., McHugh, N. J. and Mease, P. J., 2015. Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014. The Journal of Rheumatology

Tillett, W., Shaddick, G., Askari, A., Cooper, A., Creamer, P., Clunie, G., Helliwell, P. S., Kay, L., Korendowych, E., Lane, S., Packham, J., Shaban, R., Williamson, L. and McHugh, N., 2015. Factors influencing work disability in psoriatic arthritis:first results from a large UK multicentre study. Rheumatology, 54 (1), pp. 157-162.

Becker, K., Tillett, W., Price, E., Collins, D. and Williamson, L., 2014. Patient information leaflets:a study of patient and physician satisfaction. JCR : Journal of Clinical Rheumatology, 20 (8), p. 453.

de Wit, M., Campbell, W., FitzGerald, O., Gladman, D. D., Helliwell, P. S., James, J., Lindsay, C., MacDonald, R., McHugh, N. J., Mease, P. J., Orbai, A.-M., Palominos, P., Parkinson, A., Tillett, W. and Goel, N., 2014. Patient Participation in Psoriasis and Psoriatic Arthritis Outcome Research:A Report from the GRAPPA 2013 Annual Meeting. The Journal of Rheumatology, 41 (6), pp. 1206-11.

Tillett, W., Adebajo, A., Brooke, M., Campbell, W., Coates, L. C., Fitzgerald, O., Gossec, L., Helliwell, P., Hewlett, S., James, J., Minnock, P., Reast, A., O'Sullivan, D., de Wit, M. and McHugh, N., 2014. Patient involvement in outcome measures for psoriatic arthritis. Current Rheumatology Reports, 16 (5), pp. 1-10.

Tillett, W., Jadon, D., Shaddick, G., Robinson, G., Sengupta, R., Korendowych, E., De Vries, C.S. and McHugh, N.J., 2014. Feasibility, reliability, and sensitivity to change of four radiographic scoring methods in patients with psoriatic arthritis. Arthritis Care and Research, 66 (2), pp. 311-317.

Tillett, W., 2014. Work Disability in Psoriatic Arthritis. Thesis (Doctor of Philosophy (PhD)). University of Bath.

Tillett, W., Jadon, D., Shaddick, G., Cavill, C., Korendowych, E., De Vries, C. S. and McHugh, N., 2013. Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis. Annals of the Rheumatic Diseases, 72 (8), pp. 1358-1361.

Jadon, D., Tillett, W., Wallis, D., Cavill, C., Bowes, J., Waldron, N., Dixon, A., Sengupta, R., Barton, A., Korendowych, E. and McHugh, N. J., 2013. Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis. Rheumatology, 52 (2), pp. 261-6.

Coates, L.C., Tillett, W., Chandler, D., Helliwell, P.S., Korendowych, E., Kyle, S., McInnes, I.B., Oliver, S., Ormerod, A., Smith, C., Symmons, D., Waldron, N. and McHugh, N.J., 2013. The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics. Rheumatology, 52 (10), pp. 1754-1757.

Tillett, W. and McHugh, N., 2012. Treatment algorithms for early psoriatic arthritis:Do they depend on disease phenotype? Current Rheumatology Reports, 14 (4), pp. 334-342.

Tillett, W., De Vries, C. and McHugh, N. J., 2012. Work disability in psoriatic arthritis:a systematic review. Rheumatology, 51 (2), pp. 275-283.

Tillett, W., Costa, L., Jadon, D., Wallis, D., Cavill, C., McHugh, J., Korendowych, E. and McHugh, N. J., 2012. The ClASsification for Psoriatic ARthritis (CASPAR) criteria - A retrospective feasibility, sensitivity, and specificity study. Journal of Rheumatology, 39 (1), pp. 154-156.

Tillett, W., Shaddick, G., Korendowych, E., De Vries, C. S. and McHugh, N., 2012. Joint count reliability in psoriatic arthritis observational trials: an unreported problem. Rheumatology, 51 (7), pp. 1333-1334.

This list was generated on Mon Oct 16 14:54:48 2017 IST.

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