Aims & Learning Objectives:
This unit will familiarise the student with recent advances in molecular signalling and current areas of research which are of particular interest and importance. Knowledge gained from previous units in cell biology, and in particular molecular pharmacology, will be built upon with more advanced and specialised treatment of specific topics encompassing cellular signalling events in different model systems. The tutorials are integral to the unit, allowing for open discussion of pertinent current research papers. After taking this unit the student should have an in depth understanding of the complex interactions which occur in cellular signalling events. They should have developed the ability to read and interpret original research papers in this area in a logical and critical manner and recognise the intricacies of cellular signalling mechanisms.
Content:
An in-depth treatment of selected topics covering recent advances in molecular signalling, to include signalling events occuring in immune cells in response to cytokines and other mediators; protein interaction modules; kinase cascades; tyrosine kinases and phosphatases; lipid signalling; regulation of transcription.
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