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Department of Biology & Biochemistry, Unit Catalogue 2011/12


BB40102: Molecular mechanisms of disease

Click here for further information Credits: 6
Click here for further information Level: Masters UG & PG (FHEQ level 7)
Click here for further information Period: Semester 1
Click here for further information Assessment: CW 100%
Click here for further information Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Click here for further information Requisites: In taking this unit you cannot take BB40085 or take BB40118 or take BB40124 and before taking this unit you must take BB20024 and take BB10003 or you must have taken suitable degree units from another University.
Click here for further information Description: Aims:
To describe how a defect at the level of the gene results in an observed disease phenotype. To show how such patients can be treated with modern molecular medicine.

Learning Outcomes:
After taking this course the student should be able to:
* explain the common themes of genetic disorders, and how they relate to the overall phenotype;
* explain the principles of tools involved in diagnosis and treatment of the disorders.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Oral communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F/A.

Content:
Diseases: diabetes, glycogen storage diseases, hyperbilirubinaemia, familial hypercholesterolaemia, fibroblast growth factor receptors and skeletal dysplasia.
Diagnosis and treatment: PCR/cloning, antibody engineering, gene therapy, gene targeting in the mouse, mouse models for human disease.
Click here for further informationProgramme availability:

BB40102 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 3
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • USBB-ANM02 : MBiochem (hons) Biochemistry (Full-time with Thin Sandwich Placements) - Year 4
  • USBB-AKM05 : MBiol (hons) Molecular and Cellular Biology (Full-time with Thick Sandwich Placement) - Year 4
  • RSBB-AFM07 : Integrated PhD Postgenomic Biosciences (Biosciences Route) (Full-time) - Year 1
  • RSBB-AFM14 : Integrated PhD Postgenomic Biosciences (Developmental Biology Route) (Full-time) - Year 1
  • RSBB-AFM08 : Integrated PhD Postgenomic Biosciences (Regenerative Medicine Route) (Full-time) - Year 1
  • TSBB-AFM03 : MRes Biosciences (Full-time) - Year 1
  • TSBB-AFM14 : MRes Developmental Biology (Full-time) - Year 1
  • TXXX-AFM10 : MRes Regenerative Medicine (Full-time) - Year 1
  • TSBB-AFM06 : MSc Biosciences (Full-time) - Year 1
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1
  • TSBB-AFM05 : MSc Industrial Biotechnology and Enterprise (Full-time) - Year 2
  • TSBB-AFM09 : MSc Medical Biosciences (Full-time) - Year 1

NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.