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Department of Biology & Biochemistry, Unit Catalogue 2011/12

BB40188: Protein synthesis, folding and turnover

Click here for further information Credits: 6
Click here for further information Level: Masters UG & PG (FHEQ level 7)
Click here for further information Period: Semester 1
Click here for further information Assessment: CW20EX80
Click here for further information Supplementary Assessment: Supplementary assessment information not currently available (this will be added shortly)
Click here for further information Requisites:
Click here for further information Description: Aims:
To introduce the process of transcription in prokaryotes.
To provide an understanding of ribosome structure and mRNA translation in both prokaryotes and eukaryotes.
To advance knowledge of protein folding and the intracellular pathways of folding and post-translational modification.
To provide an in-depth understanding of the various pathways of intracellular and extracellular protein turnover.
To provide students with a critical and integrated overview of the key processes controlling the production and turnover of cellular proteins, informed by current research.

Learning Outcomes:
After taking this course the student should be able to:
* demonstrate knowledge of how bacterial gene expression is regulated at the transcriptional level and the process of translation;
* critically evaluate our current understanding of the processes involved in protein folding;
* demonstrate a thorough understanding of the pathways involved in protein turnover, and analyse its significance in cellular processes;
* analyse the strengths and limitations for current predictive methods for protein structure.

Learning and studying T/F/A, Written communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F.

Prokaryotic transcription
Protein Folding
Posttranslational modification
Protein Turnover
Computational approaches to the prediction of protein folding (practical).
Click here for further informationProgramme availability:

BB40188 is Optional on the following programmes:

Department of Biology & Biochemistry
  • RSBB-AFM19 : Integrated PhD Postgenomic Biosciences (Protein Structure & Function Route) (Full-time)
  • TSBB-AFM19 : MRes Protein Structure and Function (Full-time)
  • TSBB-AFM13 : MSc Protein Structure and Function (Full-time)

NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.