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Department of Biology & Biochemistry, Unit Catalogue 2011/12


BB20149: Molecular genetics of vertebrate development

Click here for further information Credits: 6
Click here for further information Level: Intermediate (FHEQ level 5)
Click here for further information Period: Semester 1
Click here for further information Assessment: EX 60%, PR 40%
Click here for further information Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Click here for further information Requisites: Before taking this unit you must take BB10006
Click here for further information Description: Aims:
To introduce the study of comparative animal development and to acquaint students with molecular basis and genetics of animal development. The genetic pathways and regulation of gene expression during embryonic development and methods to study these will be covered.

Learning Outcomes:
After taking this course the student should be able to:
* demonstrate a knowledge of the developmental processes across a wide range of species;
* demonstrate an understanding of the genes and pathways regulating development;
* demonstrate a knowledge of the current approaches in the study of gene expression, overexpression and ablation and their relevance to development carry out cytochemical, immunohistochemical and in situ hybridisation procedures.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Data acquisition, handling and analysis T/F/A, Laboratory skills T/F, Information technology T/F, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F.

Content:
Animal development covering gametogenesis and fertilisation, early development, mammalian preimplantation development, stem cells, embryonal carcinoma cells, transgenesis and targeted mutagenesis, extraembryonic membranes, X-chromosome inactivation, imprinting, regulation of gene expression, comparative genomics, large scale mutagenesis, cell adhesion, cell movement, morphogenesis and gastrulation.
Laboratory practical sessions covering , cytochemistry, in situ hybridisation and immunohistochemistry of mouse and fish embryos.
Click here for further informationProgramme availability:

BB20149 is Compulsory on the following programmes:

Department of Biology & Biochemistry
  • TSBB-AFM07 : MSc Developmental Biology (Full-time) - Year 1

BB20149 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc (hons) Biochemistry (Full-time) - Year 2
  • USBB-AKB06 : BSc (hons) Biochemistry with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • USBB-AFB03 : BSc (hons) Biology (Full-time) - Year 2
  • USBB-AKB07 : BSc (hons) Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • USBB-AFB05 : BSc (hons) Molecular and Cellular Biology (Full-time) - Year 2
  • USBB-AKB08 : BSc (hons) Molecular and Cellular Biology with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • RSBB-AFM14 : Integrated PhD Postgenomic Biosciences (Developmental Biology Route) (Full-time) - Year 1
  • RSBB-AFM08 : Integrated PhD Postgenomic Biosciences (Regenerative Medicine Route) (Full-time) - Year 1
  • TSBB-AFM14 : MRes Developmental Biology (Full-time) - Year 1
  • TXXX-AFM10 : MRes Regenerative Medicine (Full-time) - Year 1

NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.