Department of Chemistry, Unit Catalogue 2011/12 |
|
 Credits:
| 6 |
| Level:
| Intermediate (FHEQ level 5) |
| Period: |
Semester 1 |
| Assessment:
| CW 20%, EX 80% |
| Supplementary Assessment: | CH20160 - Examination (where allowed by programme regulations) |
| Requisites:
| Before taking this unit you must take CH10135 and while taking this unit you must take CH20149 |
| Description:
| Aims: The Unit will provide an introduction to the properties of drugs and some of the key aspects of medicinal chemistry which need to be considered by chemists involved in synthesising new drug molecules. Learning Outcomes: After studying the Unit, students should be able to: * identify common features of drug molecules; * manipulate data to establish biokinetic parameters; * illustrate the utility of 'log P' values and the importance of drug solubility; * describe structure/activity relationships and understand how this aids the drug discovery process. Skills: Numeracy (F, A), Problem solving (T, F, A), Scientific writing (F, A), Independent working (F), Group working (F). Content: Properties of drugs described by the Lapinski rules. Introduction to bikinetics. Definition and use of log P and its relevance to bioavailability. Structure/activity relationships. Overview of successful drugs. Interactions of drug molecules with DNA and RNA. |
| Programme availability: |
CH20160 is Compulsory on the following programmes:Department of Chemistry
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