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Department of Chemistry, Unit Catalogue 2011/12


CH30065: Biosynthesis & biotransformations

Click here for further information Credits: 3
Click here for further information Level: Honours (FHEQ level 6)
Click here for further information Period: Semester 2
Click here for further information Assessment: EX 100%
Click here for further information Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Click here for further information Requisites: Before taking this unit you must take CH30128
Click here for further information Description: Aims:
To provide an introduction to advanced aspects of a topic of current interest in Organic Chemistry.

Learning Outcomes:
After studying this Unit, students should be able to:
* Provide examples of biosynthetic pathways.
* Describe how enzymes can be used to produce enantiomerically pure compounds.

Skills:
Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F).

Content:
Biotransformations. The use of enzymes in organic synthesis. Kinetic resolution with hydrolytic enzymes, and the preparation of enantiomerically enriched alcohols and acids. Enzymes in oxidation, reduction and C-C bond forming reactions. Biosynthetic pathways, including the biosynthesis of fatty acids and polyketides. Terpene biosynthesis, the shikimic acid pathway and the roles of pyridoxal phosphate in biosynthesis are also addressed.
Click here for further informationProgramme availability:

CH30065 is Compulsory on the following programmes:

Department of Chemistry
  • USCH-AFB07 : BSc (hons) Chemistry for Drug Discovery (Full-time) - Year 3
  • USCH-AKB08 : BSc (hons) Chemistry for Drug Discovery with Industrial Training (Full-time with Thick Sandwich Placement) - Year 4
  • USCH-AAB08 : BSc (hons) Chemistry for Drug Discovery with Study Year abroad (Full-time with Study Year Abroad) - Year 4
  • USCH-AFM05 : MChem (hons) Chemistry for Drug Discovery (Full-time) - Year 3

CH30065 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFB01 : BSc (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKB02 : BSc (hons) Natural Sciences with Industrial Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAB02 : BSc (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4
  • UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 3
  • UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 4
  • UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 4

NB. Programmes and units are subject to change at any time, in accordance with normal University procedures.