Department of Pharmacy & Pharmacology, Unit Catalogue 2011/12 |
|
 Credits:
| 6 |
| Level:
| Honours (FHEQ level 6) |
| Period: |
Semester 2 |
| Assessment:
| EX100 |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| Before taking this unit you must take PA10281 and take PA20285 and take PA30286 |
| Description:
| Aims: To learn about (a) non-oral routes of drug delivery, (b) advanced drug delivery systems (c) delivery of biopharmaceuticals and (d) integration of physiology with dosage forms and pharmacokinetics. Learning Outcomes: By the end of the unit the student will be able to: 1. Compare and contrast the non-oral routes of drug delivery (nasal, pulmonary, vaginal, sublingual, buccal, topical and transdermal). Analyze which route of administration is more appropriate for a given drug therapy. Evaluate the requirements imposed to medicines by the desired route of administration. 2. Compare and contrast the dosage forms used to deliver drugs via the non-oral routes of drug delivery. Examine the key technology parameters involved in their formulation and performance. 3. Evaluate and differentiate advanced drug delivery systems: oral (enteric, delayed and controlled release), implantable, and liposome, nanoparticle - based medicines. 4. Analyse the challenges involved in delivery biopharmaceuticals. 5. Illustrate how disease and drug interactions modifies drug pharmacokinetics 6. Integrate physiology with dosage forms performance. Skills: 1. Data analysis and integration 2. Problem solving 3. Analytical thinking 4. Scientific skills 5. Handling information 6. Lateral thinking 7. Professional All taught and assessed Content: 1. The nasal and pulmonary routes of drug delivery. Related dosage forms: Inhalers. 2. Other routes of drug delivery: vaginal, sublingual, buccal. 3. The transdermal and topical route of drug delivery. Related dosage forms. 4. Advanced oral delivery systems: enteric, delayed and controlled DDS 5. Advanced parenteral drug delivery systems. Implantable dosage forms 6. Targeted drug delivery systems. 7. Biopharmaceuticals: peptides, proteins, vaccines, antibodies, gene and DNA 8. Effect of disease and drug interaction on pharmacokinetics. 9. Integration: physiology, dosage form and pharmacokinetics. |
| Programme availability: |
PA30287 is a Designated Essential Unit on the following programmes:Department of Pharmacy & Pharmacology
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