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BB20110: DNA (making, breaking & disease) [for Natural Scientists]

Follow this link for further information on academic years Academic Year: 2012/3
Follow this link for further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Follow this link for further information on credits Credits: 6
Follow this link for further information on unit levels Level: Intermediate (FHEQ level 5)
Follow this link for further information on period slots Period: Semester 1
Follow this link for further information on unit assessment Assessment: EX 60%, MC 20%, PR 20%
Follow this link for further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Follow this link for further information on unit rules Requisites: This unit is only available to students on Natural Sciences programmes.
Follow this link for further information on unit content Description: Aims:
To provide an in-depth understanding of the relationship between DNA synthesis, damage & repair mechanisms in relation to cell cycle and apoptosis. Also provides an understanding of how disruption of normal cellular function leads to disease processes, especially cancer.

Learning Outcomes:
After taking this course the student should be able to:
* give a detailed account of DNA replication, damage and repair in prokaryotic and eukaryotic systems;
* describe and explain the cross talk between cell cycle and apoptosis in relation to oncogenesis;
* explain the rationale behind tumour therapy, either conventional approaches of radio/chemotherapy or newer approaches of genetherapy, immunotherapy, angiotherapy etc.

Skills:
Learning and studying T/F/A, Written communication T/F/A, Laboratory skills T/F, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F.

Content:
DNA replication and repair in relation to disease. Role of cell cycle and apoptosis in oncogenesis. Various modes of cancer therapy.
Follow this link for further information on programme availabilityProgramme availability:

BB20110 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFB01 : BSc (hons) Natural Sciences (Full-time) - Year 2
  • UXXX-AKB02 : BSc (hons) Natural Sciences with Industrial Placement (Full-time with Thick Sandwich Placement) - Year 2
  • UXXX-AAB02 : BSc (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 2
  • UXXX-AFM01 : MSci (hons) Natural Sciences (Full-time) - Year 2
  • UXXX-AKM02 : MSci (hons) Natural Sciences with Professional Placement (Full-time with Thick Sandwich Placement) - Year 2
  • UXXX-AAM02 : MSci (hons) Natural Sciences with Study Year Abroad (Full-time with Study Year Abroad) - Year 2

Notes:
* This unit catalogue is applicable for the 2012/13 academic year only. Students continuing their studies into 2013/14 and beyond should not assume that this unit will be available in future years in the format displayed here for 2012/13.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.