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PA30266: Pharmacology of infection & immunity

Follow this link for further information on academic years Academic Year: 2014/5
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 12
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period: Academic Year
Further information on unit assessment Assessment Summary: CW 20%, EX 80%
Further information on unit assessment Assessment Detail:
  • Essay 1 (CW 10%)
  • Essay 2 (CW 10%)
  • Examination (EX 80%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
To familiarise the students with the pathogenic mechanisms of infectious disease, the human host response to infection and the pharmacology of anti-infective agents; to describe the molecular and cellular mechanisms associated with acute and chronic inflammation, to illustrate the pathology of chronic inflammatory diseases and to introduce the pharmacology of anti-inflammatory and immunosuppressive drugs; to illustrate clinical cases through problem-based learning.

Learning Outcomes:
After taking this unit, the student will demonstrate an understanding of 1) the innate, inflammatory and adaptive host defence mechanisms against infectious agents in man; 2) the key features required by micro-organisms to cause human disease and how the relevant prominence of virulence determinants contributes to the type of disease caused; 3) the role of excessive stimulation of host defence mechanisms in themselves causing human disease; 4) the pharmacology of agents targeted at the exogenous infection or endogenous host defence response, and 5) the student will be able to give a short oral presentation based on group study of appropriate clinical cases.

Scientific and practical skills (T/F/A)
Study skills, handling information, working with others (T/F)
Oral communication skills (T/F)
Problem solving (T/F)
Written skills (T/F/A)

This course introduces the concept of how micro-organisms cause infectious disease. It outlines the general defence mechanisms of the human body against infection and the ways in which micro-organisms defeat these systems. A number of paradigms of infectious diseases will be used to illustrate the critical stages of pathogenesis, namely adhesion, replication, evasion of host defences and damage to the host. Pharmacology of anti-bacterial, anti-viral, and other anti-infective compounds. Mechanisms of acute and chronic inflammation, inflammatory diseases and their treatment. An introduction of the role of the immune system in chronic inflammation.
Further information on programme availabilityProgramme availability:

PA30266 is Compulsory on the following programmes:

Department of Pharmacy & Pharmacology
  • USPA-AFB02 : BSc(Hons) Pharmacology (Year 2)
  • USPA-AKB02 : BSc(Hons) Pharmacology with Year long work placement (Year 2)
  • USPA-AKM02 : MPharmacol(Hons) Pharmacology with Year long work placement (Year 2)

PA30266 is Optional on the following programmes:

Programmes in Natural Sciences
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Year 3)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences with Study year abroad (Year 4)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences with Year long work placement (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Year 3)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences with Professional Placement (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences with Study year abroad (Year 4)

* This unit catalogue is applicable for the 2014/15 academic year only. Students continuing their studies into 2015/16 and beyond should not assume that this unit will be available in future years in the format displayed here for 2014/15.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.