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BB20219: Genomics 1

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Further information on credits Credits: 6
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take BB10007 OR take BB10214
Further information on descriptions Description: Aims:
To introduce students to the concepts of genomics.

Learning Outcomes:
After taking this course the student should be able to:
* Explain how genome sequences are generated, analysed and annotated
* Describe the type of biological information that is contained within an annotated genome sequence
* Describe the gross differences between features of genome sequences from different types of organisms
* Explain how to effectively access publicly accessible genomic resources using web portals to obtain relevant genomic information.

Skills:
Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F

Content:
Genome sequencing of bacteria and eukaryotes; Sequencing, genome assembly, and genome annotation; Sequence alignment; Comparative genomics in bacteria and eukaryotes and its applications; Uses of comparative genomics on gene and exon annotation, interpretation of variation in sequence rate of evolution (protein rates of evolution, dN/dS); Gene family evolution and gene turnover patterns; Whole genome sequence alignment and the identification of ultra-conserved regions, genomic rearrangements, horizontal gene transfer, and intra-species genomic variation; Analyses of human migration and genome-wide association studies; Non-human intra-species variation (parasites, pathogens, etc.); Forensic genomics, microsatellites, SNPs, and copy number variation; Metagenomics biodiversity and microbiomes; Biodiversity, effects of climate change and pollution on biodiversity, bioremediation, human microflora interactions, effects of lifestyle and diet on microflora.
Further information on programme availabilityProgramme availability:

BB20219 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
  • USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
  • USBB-AFB03 : BSc(Hons) Biology (Year 2)
  • USBB-AKB07 : BSc(Hons) Biology with Professional Placement (Year 2)
  • UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
  • USBB-AFB05 : BSc(Hons) Molecular and Cellular Biology (Year 2)
  • USBB-AKB08 : BSc(Hons) Molecular and Cellular Biology with Professional Placement (Year 2)

Notes:
* This unit catalogue is applicable for the 2015/16 academic year only. Students continuing their studies into 2016/17 and beyond should not assume that this unit will be available in future years in the format displayed here for 2015/16.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.