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BB20220: Genomics 2

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Biology & Biochemistry
Further information on credits Credits: 6
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment Summary: CW 20%, EX 80%
Further information on unit assessment Assessment Detail:
  • Workshop 1 (CW 10%)
  • Workshop 2 (CW 10%)
  • Examination (EX 80%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take BB10007 OR take BB10214
Further information on descriptions Description: Aims:
To introduce students to further concepts of genomics relevant to transcriptomics and proteomics.

Learning Outcomes:
After taking this course the student should be able to:
* Explain how whole genome transcriptome information is generated and analysed
* Explain the type of biological information that is contained in genome level gene expression profiles
* Relate gene expression profiles to the basic mechanisms of regulating gene expression
* Explain how gene expression profiling can be used to investigate some disease processes.

Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F

Genome wide assessment of gene expression; Comparison of transcriptome data to identify aberrant gene expression patterns of genes and/or pathways in disease states; Comparative genomics combined with transcriptomics to gain insights into the molecular basis of clinically-relevant traits; Proteomics, structural genomics, protein disorder; Gene co-expression and protein-protein networks as means to identify functional interactions among genes; Epigenetics and disease, imprinting and genome-wide assessments of epigenetic markers; Applications of genomics analyses and ethical considerations: Legal applications, pharmacogenomics (diagnostic tools and treatment development), GM crops, etc.
Further information on programme availabilityProgramme availability:

BB20220 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
  • USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
  • USBB-AFB03 : BSc(Hons) Biology (Year 2)
  • USBB-AKB07 : BSc(Hons) Biology with Professional Placement (Year 2)
  • UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
  • USBB-AFB05 : BSc(Hons) Molecular and Cellular Biology (Year 2)
  • USBB-AKB08 : BSc(Hons) Molecular and Cellular Biology with Professional Placement (Year 2)

* This unit catalogue is applicable for the 2015/16 academic year only. Students continuing their studies into 2016/17 and beyond should not assume that this unit will be available in future years in the format displayed here for 2015/16.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.