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CE40169: Molecular and cellular biochemical engineering

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Chemical Engineering
Further information on credits Credits: 6
Further information on unit levels Level: Masters UG & PG (FHEQ level 7)
Further information on teaching periods Period: Semester 1
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
To provide an understanding of how the properties of biologically active molecules and cells can be exploited for the development of biologically-derived products, novel tissue constructs, reactor systems, analytical devices and drug delivery devices.

Learning Outcomes:
After completing this unit, students should be able to demonstrate an understanding of the concepts and theories relating to the biospecific molecular interactions that can occur in biochemical systems at different scales. They should be aware of how biological components can be incorporated into composite devices developed for analytical and drug release applications and how models describing the fundamental interactions can be used in the design of such systems. They should appreciate the significance of quantitative and qualitative cellular properties including structure, function and signalling mechanisms in cell-based therapies. They should be able to carry out qualitative and quantitative analysis of enzymatic systems.

Analysis and problem solving (taught/facilitated and assessed).

Introduction to binding molecules. Use of binding molecules in drug targeting. Derivation of ligand receptor binding expressions, development of kinetic models for multi-substrate and reversible enzyme catalysed reactions. Methods of protein immobilisation and effects on intrinsic and kinetic properties. Use of enzymes in analytical devices and the significance of mass transfer limitations. The design and synthesis of scaffold materials for tissue engineering applications. Cell signalling mechanisms and pathways. Diffusion and mass transfer in cellular systems. Development of responsive hydrogels for use in "intelligent" drug delivery systems. Design and application of biosensors, biofuel cells, and bio-nanotechnology.
Further information on programme availabilityProgramme availability:

CE40169 is Compulsory on the following programmes:

Department of Chemical Engineering
  • UECE-AFM01 : MEng(Hons) Biochemical Engineering (Year 4)
  • UECE-AKM01 : MEng(Hons) Biochemical Engineering with Year long work placement (Year 5)

CE40169 is Optional on the following programmes:

Department of Chemical Engineering
  • UECE-AFM05 : MEng(Hons) Chemical Engineering (Year 4)
  • UECE-AKM05 : MEng(Hons) Chemical Engineering with Year long work placement (Year 5)

* This unit catalogue is applicable for the 2015/16 academic year only. Students continuing their studies into 2016/17 and beyond should not assume that this unit will be available in future years in the format displayed here for 2015/16.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.