|
 Academic Year:
| 2015/6 |
| Owning Department/School:
| Department of Chemistry |
| Credits:
| 3 |
| Level:
| Masters UG & PG (FHEQ level 7) |
| Period: |
Semester 2 |
| Assessment Summary:
| EX 100% |
| Assessment Detail: |
|
| Supplementary Assessment: |
Like-for-like reassessment (where allowed by programme regulations) |
| Requisites: |
Before taking this module you must take CH20149 OR take CH20150
In taking this module you cannot take CH30068 |
| Description:
| Aims: To revise some basic concepts in physical organic chemistry and develop a number of ideas used to correlate reactivity and mechanism in a range of organic reactions. Learning Outcomes: After studying the Unit, students should be able to: * Describe some experimental tools for investigating reaction mechanisms and the use of some theoretical models for their correlation and interpretation * Suggest solutions for complex problems involving combinations of numerical and mechanistic information from a variety of sources. * Propose appropriate experimental approaches for determination of organic reaction mechanisms. Skills: Problem solving (T, F, A), Scientific writing (F, A), Independent working (F). Content: Energy changes in equilibria and reactivity. Transition states and saddle points. Activation parameters. Analysis of reaction coordinates. Principle of Least Nuclear Motion. Hammond Postulate. More O¿Ferrall - Jencks diagrams. Rate - equilibrium correlations. Hammett equation as an example of a linear free-energy relationship. Significance of s and rfor reactivity and mechanism. Complex Hammett plots: change in mechanism vs. change in rate-determining step. Equilibrium and kinetic isotope effects. Primary and secondary effects and their significance. Heavy-atom effects. Solvent isotope effects. |
| Programme availability: |
CH40068 is Optional on the following programmes:Department of Chemistry
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