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PA20024: Applied pharmaceutical microbiology

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6
Further information on unit levels Level: Intermediate (FHEQ level 5)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment Summary: EX 100%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100% - Qualifying Mark: 40)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites:
Further information on descriptions Description: Aims:
To introduce the principles of control of microbial contamination and sterilisation as applied to pharmaceutical products.

Learning Outcomes:
After taking this unit the student should be able to:
1. explain the microbiological and physico-chemical properties of non-antibiotic antimicrobial agents and justify their use in pharmaceutical formulation and
2. the principles and the technology of the various methods of sterilising pharmaceutical products and the illustrate the associated procedures concerned with quality assurance.

Scientific and practical skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F/A).

Sources of microbial contamination. Kinetics of microbial inactivation and the construction and interpretation of survivor curves. Disinfectants, antiseptics and preservatives; their modes of action, assessment of efficacy and formulation parameters. Introduction to sterilisation methods; comparative advantages and disadvantages of heat, irradiation, gaseous and filtration methods. Validation of all methods. Pyrogens. Sterility testing. Facility Design.
Further information on programme availabilityProgramme availability:

PA20024 is a Designated Essential Unit on the following programmes:

Department of Pharmacy & Pharmacology
* This unit catalogue is applicable for the 2015/16 academic year only. Students continuing their studies into 2016/17 and beyond should not assume that this unit will be available in future years in the format displayed here for 2015/16.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.