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PA30287: Medicines design 3: advanced drug delivery

Follow this link for further information on academic years Academic Year: 2015/6
Further information on owning departmentsOwning Department/School: Department of Pharmacy & Pharmacology
Further information on credits Credits: 6
Further information on unit levels Level: Honours (FHEQ level 6)
Further information on teaching periods Period: Semester 2
Further information on unit assessment Assessment Summary: EX 100%, OT 0%
Further information on unit assessment Assessment Detail:
  • Examination (EX 100%)
  • Workshops attendance (OT 0%)
Further information on supplementary assessment Supplementary Assessment: Like-for-like reassessment (where allowed by programme regulations)
Further information on requisites Requisites: Before taking this module you must take PA10281 AND take PA20285 AND take PA30286
Further information on descriptions Description: Aims:
To learn about (a) non-oral routes of drug delivery, (b) advanced drug delivery systems (c) delivery of biopharmaceuticals and (d) integration of physiology with dosage forms and pharmacokinetics.

Learning Outcomes:
By the end of the unit the student will be able to:
1. Compare and contrast the non-oral routes of drug delivery (nasal, pulmonary, vaginal, sublingual, buccal, topical and transdermal). Analyze which route of administration is more appropriate for a given drug therapy. Evaluate the requirements imposed to medicines by the desired route of administration.
2. Compare and contrast the dosage forms used to deliver drugs via the non-oral routes of drug delivery. Examine the key technology parameters involved in their formulation and performance.
3. Evaluate and differentiate advanced drug delivery systems: oral (enteric, delayed and controlled release), implantable, and liposome, nanoparticle - based medicines.
4. Analyse the challenges involved in delivery biopharmaceuticals.
5. Illustrate how disease and drug interactions modifies drug pharmacokinetics
6. Integrate physiology with dosage forms performance.

1. Data analysis and integration
2. Problem solving
3. Analytical thinking
4. Scientific skills
5. Handling information
6. Lateral thinking
7. Professional
All taught and assessed

1. The nasal and pulmonary routes of drug delivery. Related dosage forms: Inhalers.
2. Other routes of drug delivery: vaginal, sublingual, buccal.
3. The transdermal and topical route of drug delivery. Related dosage forms.
4. Advanced oral delivery systems: enteric, delayed and controlled DDS
5. Advanced parenteral drug delivery systems. Implantable dosage forms
6. Targeted drug delivery systems.
7. Biopharmaceuticals: peptides, proteins, vaccines, antibodies, gene and DNA
8. Effect of disease and drug interaction on pharmacokinetics.
9. Integration: physiology, dosage form and pharmacokinetics.
Further information on programme availabilityProgramme availability:

PA30287 is a Designated Essential Unit on the following programmes:

Department of Pharmacy & Pharmacology
* This unit catalogue is applicable for the 2015/16 academic year only. Students continuing their studies into 2016/17 and beyond should not assume that this unit will be available in future years in the format displayed here for 2015/16.
* Programmes and units are subject to change at any time, in accordance with normal University procedures.
* Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.