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BB20219: Genomics 1

[Page last updated: 04 August 2021]

Academic Year: 2021/2
Owning Department/School: Department of Biology & Biochemistry
Credits: 6 [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Intermediate (FHEQ level 5)
Period:
Semester 1
Assessment Summary: EX 100%
Assessment Detail:
  • Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take BB10007 OR take BB10214 OR take BB10264
Aims: To introduce students to the concepts of genomics.

Learning Outcomes: After taking this course the student should be able to:
* Explain how genome sequences are generated, analysed and annotated
* Describe the type of biological information that is contained within an annotated genome sequence
* Describe the gross differences between features of genome sequences from different types of organisms
* Explain how to effectively access publicly accessible genomic resources using web portals to obtain relevant genomic information.

Skills: Knowledge and understanding T/F/A, Intellectual skills F/A, Written communication T/F/A, Numeracy F/A, Data acquisition, handling, and analysis T/F/A, Information technology T/F, Working independently T/F

Content: Genome sequencing of bacteria and eukaryotes; Sequencing, genome assembly, and genome annotation; Sequence alignment; Comparative genomics in bacteria and eukaryotes and its applications; Uses of comparative genomics on gene and exon annotation, interpretation of variation in sequence rate of evolution (protein rates of evolution, dN/dS); Gene family evolution and gene turnover patterns; Whole genome sequence alignment and the identification of ultra-conserved regions, genomic rearrangements, horizontal gene transfer, and intra-species genomic variation; Analyses of human migration and genome-wide association studies; Non-human intra-species variation (parasites, pathogens, etc.); Forensic genomics, microsatellites, SNPs, and copy number variation; Metagenomics biodiversity and microbiomes; Biodiversity, effects of climate change and pollution on biodiversity, bioremediation, human microflora interactions, effects of lifestyle and diet on microflora.

Programme availability:

BB20219 is Optional on the following programmes:

Department of Biology & Biochemistry
  • USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
  • USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
  • USBB-AFB03 : BSc(Hons) Biology (Year 2)
  • USBB-AKB07 : BSc(Hons) Biology with Professional Placement (Year 2)
  • UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
  • USBB-AFM06 : MBiochem(Hons) Biochemistry (Year 2)
  • USBB-AKM06 : MBiochem(Hons) Biochemistry with Professional Placement (Year 2)
  • USBB-AFM07 : MBiol(Hons) Biology (Year 2)
  • USBB-AKM07 : MBiol(Hons) Biology with Professional Placement (Year 2)
  • UXXX-AFM11 : MBioMed(Hons) Biomedical Sciences (Year 2)
  • UXXX-AKM11 : MBioMed(Hons) Biomedical Sciences with Professional Placement (Year 2)
Programmes in Natural Sciences
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Biology with Physics stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Biology with Physics stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Biology with Physics stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 2)
  • UXXX-AFB01 : BSc(Hons) Natural Sciences (Physics with Biology stream) (Year 2)
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Physics with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKB02 : BSc(Hons) Natural Sciences (Physics with Biology stream) with Year long work placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Physics stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Professional Placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 2)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Biology stream) (Year 2)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Study year abroad (Year 2)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Professional Placement (Year 2)

Notes:

  • This unit catalogue is applicable for the 2021/22 academic year only. Students continuing their studies into 2022/23 and beyond should not assume that this unit will be available in future years in the format displayed here for 2021/22.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.