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PA20320: Specialised integrated unit 3: management of respiratory diseases and dermatology

[Page last updated: 05 August 2021]

Academic Year: 2021/2
Owning Department/School: Department of Pharmacy & Pharmacology
Credits: 12 [equivalent to 24 CATS credits]
Notional Study Hours: 240
Level: Intermediate (FHEQ level 5)
Period:
Semester 2
Assessment Summary: CW 30%, EX 70%
Further information on unit assessment Assessment Detail:
  • Assessment detail data for this unit is currently being updated as a change has been approved. Updated assessment information will be published here shortly.
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: While taking this module you must take PA20318 AND take PA20319 AND take PA20321 AND take PA20322
Description: Aims:
To provide a comprehensive, integrated understanding of the design and development of medicines, their pharmacological actions in the body and the evidence-based approach to treatment of patients with the aim of promoting safe and effective outcomes in respiratory diseases and dermatological disorders.

Learning Outcomes:
After successfully completing this unit, the student pharmacist will be able to:
1. Describe the aetiology, epidemiology, pathophysiology and clinical symptoms of respiratory diseases and how they are diagnosed and treated.
2. Explain the impact of genetic variation on human health and techniques for its detection and analysis
3. Explain the pharmacology and mechanisms of action of medicines used for the treatment of respiratory and dermatological conditions and be able to critically evaluate structure-activity relationships, dose-response relationships, biomarkers of treatment and clinical outcomes
4. Understand the ADME, formulation and manufacturing challenges in the development and production of pulmonary and topical drug delivery systems
5. Describe the formulation and requirements of inhaled and topical dosage forms and their application in treating respiratory and dermatological conditions
6. Identify and utilise evidence-based approaches for the management of respiratory diseases and dermatological disorders.
7. Describe the role of the pharmacist in prescribing, administering and monitoring medication for patients with respiratory diseases and dermatological disorders
8. Evaluate the evidence base for the management of respiratory diseases and dermatological disorders.
9. Make appropriate clinical decisions in support of patients with respiratory diseases and dermatological disorders.
10. Apply structured consultation skills to the conditions studied in this unit.

Skills:
Scientific and practical skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F/A)
Study skills (T/F)
Handling information (T/F/A)
Written communication (T/F/A)
Scientific & practical skills (T/F/A)
Information & communication technology (ICT) (T/F)

Content:
Content to include:
Clinical Introduction and overview of therapeutic area - Problem-based learning case
* Pharmaceutics theme
- Biopharmaceutics of pulmonary drug delivery
- Deposition mechanisms in the lung
- Inhalation devices
- Biopharmaceutics of topical drug delivery to the skin
- Dermatological formulations. Emulsions, creams, ointments and other colloidal systems
- Biopharmaceutics of nasal, ocular and otic drug delivery
* Pharmacology theme
- Autonomic nervous system pharmacology
- Acute inflammation in respiratory allergy and asthma
- Gene transcription, inherited genetic diseases including cystic fibrosis.
* Medicinal Chemistry and drug design theme
- Drug design - Steroids (II), beta agonists, structure-activity relationships
- Chemistry of steroids (II)
* Clinical therapeutics theme
- Allergy, hay fever, asthma and COPD
- Inflammatory and infective skin diseases
- Wound management and dressings
- Clinical decision making in respiratory diseases and dermatology
* Simulation and practice-based learning in respiratory disease.

Programme availability:

PA20320 is a Designated Essential Unit on the following programmes:

Department of Pharmacy & Pharmacology
  • USPA-AFM03 : MPharm(Hons) Pharmacy (Year 2)
  • USPA-AKM03 : MPharm(Hons) Pharmacy with integrated pre-registration year (Year 2)

Notes:

  • This unit catalogue is applicable for the 2021/22 academic year only. Students continuing their studies into 2022/23 and beyond should not assume that this unit will be available in future years in the format displayed here for 2021/22.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.