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BB40128: The evolution of genetic systems

[Page last updated: 02 August 2022]

Academic Year: 2022/23
Owning Department/School: Department of Biology & Biochemistry
Credits: 6 [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Masters UG & PG (FHEQ level 7)
Period:
Semester 1
Assessment Summary: CW 40%, EX 60%
Assessment Detail:
  • Coursework (CW 40%)
  • Examination (EX 60%)
Supplementary Assessment:
Re-assessment Essay (where allowed by programme regulations)
Requisites: Before taking this module you are advised to take BB20040 and have A-level Mathematics (or equivalent).
Learning Outcomes: After taking this course the student should be able to:
* demonstrate competence in the analysis of simple recursion equations as applied to one locus problems;
* explain the operation of two locus recursion equations with application to modifier analysis;
* explain the methods for testing evolutionary hypotheses;
* explain basic concepts within evolutionary genetic and molecular evolution.

Aims: To provide an introduction to mathematical population genetics and its application as regards understanding problems related to the organisation and structure of genetic systems.

Skills: Learning and studying T/F/A, Written communication T/F/A, Oral communication T/F/A, Information handling & retrieval T/F/A, Working independently T/F.

Content: The first four lectures provide an introduction to the mathematics of gene frequency change. This provides the basis for asking the following questions:
1) Why do organisms have sex? 2) What determines the mutation rate? and 3) Why are mutations recessive? After this the notion of selfish elements is introduced and their relevance to understanding the number of sexes and to genome structure is examined. Use of molecular evolutionary data comparative analysis and experimental tests of hypotheses are discussed.

Programme availability:

BB40128 is Optional on the following programmes:

Department of Biology & Biochemistry Programmes in Natural Sciences
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Physics stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Physics stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Physics with Biology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Physics with Biology stream) with Professional Placement (Year 5)

Notes:

  • This unit catalogue is applicable for the 2022/23 academic year only. Students continuing their studies into 2023/24 and beyond should not assume that this unit will be available in future years in the format displayed here for 2022/23.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.