BB20018: Enzymology
[Page last updated: 02 August 2022]
| Academic Year: | 2022/23 |
| Owning Department/School: | Department of Biology & Biochemistry |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Semester 2
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| Assessment Summary: | EX 80%, PR 20% |
| Assessment Detail: |
- Practical (PR 20%)
- Examination (EX 80%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
Before taking this module you must ( take BB10003 AND take 1 MODULE FROM {BB10004, BB10121} ) OR take BB10263
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| Learning Outcomes:
| After taking this course the student should be able to:
* describe the relationship between protein structure, ligand binding and enzyme catalysis;
* explain how enzymes achieve their high catalytic rates;
* explain steady-state kinetics of enzyme-catalysed reactions, the nature of reversible inhibition, and the effects of temperature and pH;
* describe and carry out the requirements of reliable enzyme assays;
* explain allosteric regulation in the control of enzymes;
* describe the organisation of cellular enzymes into multienzyme complexes and multifunctional enzymes;
* describe the role of isoenzymes in cellular regulation, development and differentiation, and their application to diagnosis of disease;
* describe and explain the role of coenzymes in enzyme catalysis.
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| Aims: | To provide a fundamental understanding of enzymes as catalysts, at a physio-chemical level, and to relate these molecular properties to their cellular functions.
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| Skills: | Learning and studying T/F/A, Written communication T/F/A, Numeracy & computation T/F/A, Laboratory skills T/F, Information technology T/F, Problem solving T/F, Information handling & retrieval T/F/A, Working independently T/F, Career preparation T/F.
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| Content: | Ligand binding; steady-state kinetics; inhibition; effects of temperature and pH; principles of enzyme assay; theories of catalysis; allostery; isoenzymes, multienzyme complexes; coenzyme chemistry.
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| Programme availability: |
BB20018 is Compulsory on the following programmes:
Department of Biology & Biochemistry
- USBB-AFB02 : BSc(Hons) Biochemistry (Year 2)
- USBB-AKB06 : BSc(Hons) Biochemistry with Professional Placement (Year 2)
- USBB-AFM06 : MBiochem(Hons) Biochemistry (Year 2)
- USBB-AKM06 : MBiochem(Hons) Biochemistry with Professional Placement (Year 2)
Programmes in Natural Sciences
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 2)
BB20018 is Optional on the following programmes:
Department of Biology & Biochemistry
- UXXX-AFB11 : BSc(Hons) Biomedical Sciences (Year 2)
- UXXX-AKB11 : BSc(Hons) Biomedical Sciences with Professional Placement (Year 2)
- UXXX-AFM11 : MBioMed(Hons) Biomedical Sciences (Year 2)
- UXXX-AKM11 : MBioMed(Hons) Biomedical Sciences with Professional Placement (Year 2)
Programmes in Natural Sciences
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 2)
- UXXX-AAB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 2)
- UXXX-AKB02 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 2)
- UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 2)
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Notes: - This unit catalogue is applicable for the 2022/23 academic year only. Students continuing their studies into 2023/24 and beyond should not assume that this unit will be available in future years in the format displayed here for 2022/23.
- Programmes and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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