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PA40162: Drug targets in the immune system

[Page last updated: 03 August 2022]

Academic Year: 2022/23
Owning Department/School: Department of Pharmacy & Pharmacology
Credits: 6 [equivalent to 12 CATS credits]
Notional Study Hours: 120
Level: Masters UG & PG (FHEQ level 7)
Period:
Semester 2
Assessment Summary: EX 100%
Assessment Detail:
  • Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites:
Learning Outcomes: On successful completion of this unit, the student should be able to: synthesise an in-depth knowledge of recently identified target molecules and processes in the immune system, evaluate critically the role of these targets in particular therapeutic areas and utilise a range of ICT and cognitive skills in acquiring knowledge and understanding and applying them to complex, incomplete or contradictory situations.

Aims: The aims of this unit are to provide a knowledge base of recent developments in understanding the immune system and its role in human diseases, and to examine how such understanding can lead to identification and exploitation of novel drug targets for future therapy.

Skills: Scientific skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F).

Content: Following an introduction and brief overview of earlier core units, a number of topics will be discussed using the general formula of molecular target linking to cellular process linking to therapeutic area.. Topics will be selected on the basis of their currency at a given time - examples may include IgE, NF?B, PI-3 kinase, IL-23, P2X7 receptors linking to mast cell degranulation, apoptosis, chemotaxis, inflammation, inflammasome processing linking to respiratory, inflammatory and autoimmune disease states such as allergy, rheumatoid arthritis, asthma.

Programme availability:

PA40162 is Optional on the following programmes:

Department of Pharmacy & Pharmacology Programmes in Natural Sciences
  • UXXX-AAB02 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 5)
  • UXXX-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 4)
  • UXXX-AAM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 5)
  • UXXX-AKM02 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 5)

Notes:

  • This unit catalogue is applicable for the 2022/23 academic year only. Students continuing their studies into 2023/24 and beyond should not assume that this unit will be available in future years in the format displayed here for 2022/23.
  • Programmes and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.