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CH30065: Biosynthesis & biotransformations

[Page last updated: 23 October 2023]

Academic Year: 2023/24
Owning Department/School: Department of Chemistry
Credits: 3 [equivalent to 6 CATS credits]
Notional Study Hours: 60
Level: Honours (FHEQ level 6)
Period:
Semester 2
Assessment Summary: EX 100%
Assessment Detail:
  • Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take CH30128
Learning Outcomes: After studying this Unit, students should be able to:
* Provide examples of biosynthetic pathways.
* Describe how enzymes can be used to produce enantiomerically pure compounds.


Aims: To provide an introduction to advanced aspects of a topic of current interest in Organic Chemistry.

Skills: Problem solving (T, F, A). Scientific writing (F, A). Independent working (F). Group working (F).

Content: Biotransformations. The use of enzymes in organic synthesis. Kinetic resolution with hydrolytic enzymes, and the preparation of enantiomerically enriched alcohols and acids. Enzymes in oxidation, reduction and C-C bond forming reactions. Biosynthetic pathways, including the biosynthesis of fatty acids and polyketides. Terpene biosynthesis, the shikimic acid pathway and the roles of pyridoxal phosphate in biosynthesis are also addressed.

Course availability:

CH30065 is Compulsory on the following courses:

Department of Chemistry
  • USCH-AFB07 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AAB08 : BSc(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKB08 : BSc(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)
  • USCH-AFM05 : MChem(Hons) Chemistry for Drug Discovery (Year 3)

CH30065 is Optional on the following courses:

Department of Chemistry
  • USCH-AFB01 : BSc(Hons) Chemistry (Year 3)
  • USCH-AAB02 : BSc(Hons) Chemistry with Study year abroad (Year 4)
  • USCH-AKB02 : BSc(Hons) Chemistry with Industrial Placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Year long work placement (Year 4)
  • USCH-AFM02 : MChem(Hons) Chemistry (Year 3)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 4)

Notes:

  • This unit catalogue is applicable for the 2023/24 academic year only. Students continuing their studies into 2024/25 and beyond should not assume that this unit will be available in future years in the format displayed here for 2023/24.
  • Courses and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.