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CH30128: Topics in organic chemistry I

[Page last updated: 23 October 2023]

Academic Year: 2023/24
Owning Department/School: Department of Chemistry
Credits: 3 [equivalent to 6 CATS credits]
Notional Study Hours: 60
Level: Honours (FHEQ level 6)
Period:
Semester 1
Assessment Summary: EX 100%
Assessment Detail:
  • Examination (EX 100%)
Supplementary Assessment:
Like-for-like reassessment (where allowed by programme regulations)
Requisites: Before taking this module you must take CH20149 OR take CH20150
Learning Outcomes: After studying this unit students should be able to:
* Analyse the stereochemical course of a variety of reactions
* Describe reagent systems to effect a wide range of simple transformation
* Describe fully the mechanism of these reactions
* Apply the information learnt to solve problems.


Aims: The aim of the unit is to give students a thorough grounding in the methods, strategies and reagents employed in modern stereoselective organic synthesis.

Skills: Problem solving (T, F, A)
Scientific writing (F, A), Independent working (f)
Group working (F)

Content: The unit begins with a section concerned with simple diastereoselection, focusing on the reactions of carbonyl and alkene systems. The concepts of allylic strain and directed reactions are introduced. The use of chiral auxiliaries to control the stereochemistry of organic reactions forms the second section. Particular systems studied include the use of SAMP and RAMP hydrazones and Evans' auxiliaries to control a range of chiral-enolate based bond constructions.

Course availability:

CH30128 is Compulsory on the following courses:

Department of Chemistry
  • USCH-AFB01 : BSc(Hons) Chemistry (Year 3)
  • USCH-AAB02 : BSc(Hons) Chemistry with Study year abroad (Year 4)
  • USCH-AFB07 : BSc(Hons) Chemistry for Drug Discovery (Year 3)
  • USCH-AAB08 : BSc(Hons) Chemistry for Drug Discovery with Study year abroad (Year 4)
  • USCH-AKB08 : BSc(Hons) Chemistry for Drug Discovery with Industrial Placement (Year 4)
  • USCH-AKB02 : BSc(Hons) Chemistry with Industrial Placement (Year 4)
  • USCH-AFM02 : MChem(Hons) Chemistry (Year 3)
  • USCH-AFM05 : MChem(Hons) Chemistry for Drug Discovery (Year 3)

CH30128 is Optional on the following courses:

Department of Chemistry
  • USCH-AFB03 : BSc(Hons) Chemistry with Management (Year 3)
  • USCH-AAB04 : BSc(Hons) Chemistry with Management with Study year abroad (Year 4)
  • USCH-AKB04 : BSc(Hons) Chemistry with Management with Industrial Placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Environmental Science stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Physics stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Environmental Science with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 4)
  • USSC-AFB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • USSC-AAB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKB01 : BSc(Hons) Natural Sciences (Physics with Chemistry stream) with Year long work placement (Year 4)
  • USCH-AFM07 : MSci(Hons) Chemistry with Management (Year 3)
  • USCH-AKM07 : MSci(Hons) Chemistry with Management with Industrial Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Chemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biochemistry stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Biology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Physics stream) with Professional Placement (Year 4)
  • USSC-AFM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) (Year 3)
  • USSC-AAM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Study year abroad (Year 4)
  • USSC-AKM01 : MSci(Hons) Natural Sciences (Physics with Chemistry stream) with Professional Placement (Year 4)

Notes:

  • This unit catalogue is applicable for the 2023/24 academic year only. Students continuing their studies into 2024/25 and beyond should not assume that this unit will be available in future years in the format displayed here for 2023/24.
  • Courses and units are subject to change in accordance with normal University procedures.
  • Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
  • Find out more about these and other important University terms and conditions here.