SL20018: Infection and immunity for natural sciences students (PA20351)
[Page last updated: 26 October 2023]
| Academic Year: | 2023/24 |
| Owning Department/School: | Department of Life Sciences |
| Credits: | 6 [equivalent to 12 CATS credits] |
| Notional Study Hours: | 120 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Semester 2
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| Assessment Summary: | ES 20%, EX 80% |
| Assessment Detail: |
- PA20351 Essay (ES 20%)
- PA20351 Examination (EX 80%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
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| Learning Outcomes: |
After taking this unit, the student will be able to
* Describe the innate, adaptive and inflammatory host defence mechanisms against infectious agents
* List the key features required by micro-organisms to cause human disease
* Explain the role of excessive stimulation of host defence mechanisms in themselves causing human disease;
* Justify the use of pharmacology of agents targeted at the exogenous infection or endogenous host defence response,
* Explain the uses and limitations of antibodies in the laboratory and in the diagnosis and treatment of disease
* Apply their knowledge of host defence mechanisms to interpret clinical case studies
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| Aims: | To familiarise the students with the pathogenic mechanisms of infectious disease, the human host response to infection and the pharmacology of anti-infective agents; to describe the molecular and cellular mechanisms associated with acute and chronic inflammation, to illustrate the pathology of chronic inflammatory diseases and to introduce the pharmacology of anti-inflammatory and immunosuppressive drugs and biological agents; to illustrate clinical cases through problem-based learning.
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| Skills: | Scientific and practical skills (T/F/A)
Study skills, handling information, working with others (T/F)
Problem solving (T/F)
Written skills (T/F/A)
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| Content: | :
* The innate and adaptive immune system - antibodies, T and B lymphocytes, antigen presenting cells and the MHC, effector functions,
* Mechanisms by which micro-organisms cause infectious disease.
* Pharmacology of anti-infective compounds.
* Mechanisms of tolerance and autoimmunity, acute and chronic inflammation,
* Pharmacology of anti-inflammatory and anti-rheumatic agents and potential novel therapeutic approaches.
* Use of antibodies as laboratory, diagnostic and therapeutic agents.
* Problem based learning applied to relevant clinical case studies.
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| Course availability: |
SL20018 is Optional on the following courses:
Department of Chemistry
- USSC-AFB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Biology with Pharmacology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biochemistry stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Biology stream) with Year long work placement (Year 2)
- USSC-AFB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) (Year 2)
- USSC-AAB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Study year abroad (Year 2)
- USSC-AKB01 : BSc(Hons) Natural Sciences (Pharmacology with Chemistry stream) with Year long work placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Biochemistry with Pharmacology stream) with Professional Placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Biology with Pharmacology stream) with Professional Placement (Year 2)
- USSC-AFM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) (Year 2)
- USSC-AAM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Study year abroad (Year 2)
- USSC-AKM01 : MSci(Hons) Natural Sciences (Chemistry with Pharmacology stream) with Professional Placement (Year 2)
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Notes: - This unit catalogue is applicable for the 2023/24 academic year only. Students continuing their studies into 2024/25 and beyond should not assume that this unit will be available in future years in the format displayed here for 2023/24.
- Courses and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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