SL22138: Immunity and immunotherapy
[Page last updated: 09 August 2024]
| Academic Year: | 2024/25 |
| Owning Department/School: | Department of Life Sciences |
| Credits: | 10 [equivalent to 20 CATS credits] |
| Notional Study Hours: | 200 |
| Level: | Intermediate (FHEQ level 5) |
| Period: |
- Semester 2
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| Assessment Summary: | CWES 20%, EXCB 80% |
| Assessment Detail: |
- Essay (CWES 20%)
- Closed book examination (EXCB 80%)
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| Supplementary Assessment: |
- Like-for-like reassessment (where allowed by programme regulations)
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| Requisites: |
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| Learning Outcomes: |
After successfully completing this unit, students will be able to:
* Describe the innate, adaptive and inflammatory host defence mechanisms against infectious agents
* List the key features required by micro-organisms to cause human disease
* Explain the role of excessive stimulation of host defence mechanisms in themselves causing human disease;
* Justify the use of pharmacology of agents targeted at the exogenous infection or endogenous host defence response,
* Explain the uses and limitations of antibodies in the laboratory and in the diagnosis and treatment of disease
* Apply their knowledge of host defence mechanisms to interpret clinical case studies.
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| Synopsis: | Explore the pathogenic mechanisms of infectious disease, the human host response to infection and the pharmacology of anti-infective agents.
Develop an understanding of the molecular and cellular mechanisms associated with the acute inflammatory response.
Explore the pathology of chronic inflammatory diseases and investigate the pharmacology of anti-inflammatory and immunosuppressive agents.
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| Content: | The innate and adaptive immune system - antibodies, T and B lymphocytes, antigen presenting cells and the MHC, effector functions,
* Mechanisms by which micro-organisms cause infectious disease.
* Pharmacology of anti-infective compounds.
* Mechanisms of tolerance and autoimmunity, acute and chronic inflammation,
* Pharmacology of anti-inflammatory and anti-rheumatic agents and potential novel therapeutic approaches.
* Use of antibodies as laboratory, diagnostic and therapeutic agents.
* Problem based learning applied to relevant clinical case studies.
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| Course availability: |
SL22138 is Compulsory on the following courses:
Department of Chemistry
- USSC-AFB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biochemistry and Pharmacology) with professional placement (Year 2)
- USSC-AFB10 : BSc(Hons) Natural Sciences (Biology and Pharmacology) (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biology and Pharmacology) with Study year abroad (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Biology and Pharmacology) with professional placement (Year 2)
- USSC-AFB10 : BSc(Hons) Natural Sciences (Chemistry and Pharmacology) (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Chemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKB10 : BSc(Hons) Natural Sciences (Chemistry and Pharmacology) with professional placement (Year 2)
- USSC-AFM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biochemistry and Pharmacology) with professional placement (Year 2)
- USSC-AFM10 : MSci(Hons) Natural Sciences (Biology and Pharmacology) (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biology and Pharmacology) with Study year abroad (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Biology and Pharmacology) with professional placement (Year 2)
- USSC-AFM10 : MSci(Hons) Natural Sciences (Chemistry and Pharmacology) (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Chemistry and Pharmacology) with Study year abroad (Year 2)
- USSC-AKM10 : MSci(Hons) Natural Sciences (Chemistry and Pharmacology) with professional placement (Year 2)
Department of Life Sciences
- USSL-AFB13 : BSc(Hons) Pharmacology (Year 2)
- USSL-AKB13 : BSc(Hons) Pharmacology with professional placement (Year 2)
- USSL-AKM13 : MPharmacol(Hons) Pharmacology with professional placement (Year 2)
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Notes: - This unit catalogue is applicable for the 2024/25 academic year only. Students continuing their studies into 2025/26 and beyond should not assume that this unit will be available in future years in the format displayed here for 2024/25.
- Courses and units are subject to change in accordance with normal University procedures.
- Availability of units will be subject to constraints such as staff availability, minimum and maximum group sizes, and timetabling factors as well as a student's ability to meet any pre-requisite rules.
- Find out more about these and other important University terms and conditions here.
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