Mass Spectrometry is a sensitive technique used to identify and quantify compounds based on their mass, charge, structure and elemental composition. It has many applications including:

  • Organic and inorganic synthesis product confirmation
  • Protein identification
  • Impurity profiling
  • Identification of unknowns
  • Reaction monitoring
  • Environmental screening

Application notes

Learn how to routinely quantitate amino acids, with additional untargeted analysis capabilities, using mass spectrometry.

Read on to learn how TD-GC-MS can be used for the detection of volatile compounds.

Read this quick introduction to what MALDI-TOF-MS can do and how it works.

Read former mass spectrometrist Shaun's testimonial about Agilent MassHunter WalkUp software.

Our equipment

  • Automated Agilent QTOF (Walkup) used with HPLC (4 chromatography columns) for routine small molecule, peptide and intact protein analysis.

  • Agilent GC-MSD equipped with Thermal Desorption for volatile and semi-volatile organic compound (VOC, sVOC) gas chromatographic analysis.

  • Bruker MicrOTOF Electrospray Time-Of-Flight mass spectrometer (ESI-TOF) coupled to an Agilent High Performance Liquid Chromatography (HPLC) unit for the separation of mixtures, combined with accurate mass measurement. This instrument is available to trained users for Open Access use.

  • Bruker MicrOTOF Quadrupole Time-Of-Flight (ESI-QTOF) coupled to a syringe driver within a glove box, for air- and moisture-sensitive samples.

  • Bruker MaXis HD ESI-QTOF mass spectrometer for high mass accuracy, coupled to a Thermo Scientific Dionex Ultra High Performance Liquid Chromatography (UPLC) unit.

  • Bruker AutoFlex Matrix-Assisted Laser Desorption Ionisation (MALDI) mass spectrometer for polymer and peptide analysis.

  • Agilent NanoLC coupled to an Agilent ESI-QTOF mass spectrometer for proteomics applications.

Internal users

Please see our Moodle page.