Shaun Reeksting Instrument Specialist - Mass Spectrometry
Shaun facilitates research by providing training and analytical support in advanced Mass Spectrometry (MS) techniques.
Shaun supports a wide diversity of researchers, analysing compounds from small molecules and polymers, to synthetic peptides and intact proteins, by MS analysis and characterisation tools. The service he runs includes a comprehensive range of mass spec techniques, including MALDI-TOF and ESI-(Q)-TOF MS. Additional responsibilities include bespoke method development and instrument configuration, scheduled maintenance, and general administration activities. Shaun provides external consultation services through tailored analysis of by-products from industrial chemical processes, plant metabolite profiling, and identification of impurities/instability products in pharmaceutical formulations.
Shaun has several years of industry experience as an analyst and researcher in accredited ISO 17025 food safety and environmental laboratories. Laterly this included overseeing, coordinating and validating analytical methods for national food safety surveillance programs. Shaun trained analysts on sample preparation techniques, and using GC-MS and LC-MS for low level (ppt, ppb) detection of pesticide, mycotoxin, steroid and antibiotic residues in foods and feed. This focused on accuracy, traceability, internal proficiency testing, and validity of methods. Shaun moved to the University of Bath in 2016 where he routinely applies these principles in the MS service he runs, ensuring reliable, reproducible and high-quality results from a multitude of different sample matrices.
Shaun's PhD, under supervision from Prof Lyn-Marie Birkholtz (University of Pretoria, South Africa) and Prof Carsten Wrenger (Bernhard Nocht Institute for Tropical Medicine, Germany), focused on protein rational target-based drug selection and in silico or virtual drug screening, with the aim of developing improved therapeutics against malaria. This took a multidisciplinary approach including molecular parasitology, DNA microarrays, proteomics, mass spectrometry, and enzyme-kinetics and -purification methodologies.