Bath Science Café: Perfect wound repair – lessons from embryos

The Bath Science Café on Monday 13 June 2011 will look at tissue repair in embryos and what this can teach us about wound repair.

The session will be presented by Dr Will Wood, a Wellcome Trust Senior Research Fellow and Reader at the University of Bath.

Tissue repair in embryos is rapid, efficient and perfect and does not leave a scar, an ability that is lost as development proceeds.

Whereas adult wound cells from the epidermis, (the outmost layer of the skin), crawl forwards over the wound to close the gap, in an embryonic wound the epidermis is closed by contraction of the protein actin in what resembles a ‘purse string’ movement.

One key difference between embryonic and adult repair, which may explain why one heals perfectly and the other scars, is the presence of an inflammatory response at sites of adult repair where there is none in the embryo.

Dr Wood’s research team has carried out genetic studies of inflammation in Zebrafish larvae with the aim of identifying ways of improving adult healing.

Dr Wood will be discussing his research in this field, and exploring whether the inflammatory response in adult wounds may be partly responsible for scarring.

The event will take place at The Raven in the centre of Bath, and will begin at 7:30pm. For more information please visit Bath Science Café.

The official Twitter hash tag is #BathSciCafe.

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