Department of Biology & Biochemistry, Unit Catalogue 2009/10 |
BB20023: DNA (making, breaking & disease) |
 Credits:
| 6 |
| Level:
| Intermediate |
| Period: | Semester 1 |
| Assessment:
| EX 60%, MC 20%, PR 20% |
| Supplementary Assessment: | Like-for-like reassessment (where allowed by programme regulations) |
| Requisites:
| |
| Description: | Aims: To provide an in-depth understanding of the relationship between DNA synthesis, damage & repair mechanisms in relation to cell cycle and apoptosis. Also provides an understanding of how disruption of normal cellular function leads to disease processes, especially cancer. Learning Outcomes: After taking this course the student should be able to: * give a detailed account of DNA replication, damage and repair in prokaryotic and eukaryotic systems; * describe and explain the cross talk between cell cycle and apoptosis in relation to oncogenesis; * explain the rationale behind tumour therapy, either conventional approaches of radio/chemotherapy or newer approaches of genetherapy, immunotherapy, angiotherapy etc. Skills: Learning and studying T/F/A, Written communication T/F/A, Laboratory skills T/F, Information technology T/F, Information handling & retrieval T/F/A, Working independently T/F. Content: DNA replication and repair in relation to disease. Role of cell cycle and apoptosis in oncogenesis. Various modes of cancer therapy. |